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Yıl:2023; Cilt: 60; Sayı: 4>> Özet
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Nöropsikiyatri Arşivi; 2023;60(4):295-297
COVID-19 İlişkili Guillain-Barré Sendromu: Bir Nedensel İlişki Var mı Yoksa Sadece Bir Tesadüf mü?
NG Şirin
İstanbul Üniversitesi, İstanbul
Koronavirüs 19 hastalığı (COVID-19) salgını sonrası, iki hastalığın birbiriyle ilişkisini açığa çıkarmak amacıyla COVID-19 ilişkili Guillain-Barré sendromu (GBS) ile ilgili birçok vaka sunumu ve vaka serisi yayımlandı. Bu kısa bildirimde, farklı ülkelerin bölgelerinden yayınlanmış epidemiyolojik veriler gözden geçirilmiştir. COVID-19 ilişkili GBS vakalarının klinik özellikleri daha ileri yaşta olmaları, daha fazla erkek oranı ve tedaviye yanıtlı klasik duysal-motor varyant özellikleri göstermeleriydi. En sık elektrodiyagnostik alt tip demyelinizandı. Yoğun çabaya rağmen COVID-19 ile GBS arasındaki nedensel ilişki halen tartışmalıdır. COVID-19 ve GBS arasındaki ilişkiyi anlamak için yüksek hasta sayısı içeren vaka kontrol çalışmaları gereklidir
Guillain-Barré Syndrome Associated with COVID-19: Is There A Causal Relation orJust A Coincidence?
After the outbreak of Coronavirus disease 19 (COVID-19), several case reports and case series of Guillain-Barré syndrome (GBS) associated with COVID-19 have been published to unravel the possible causal link between GBS and COVID-19. In this brief report, the epidemiological data from regions in different countries was reviewed. The clinical features of GBS associated with COVID-19 was older age, male predominance, and typical sensorimotor variant responding well to treatments. The most common electrodiagnostic subtype was demyelinating. Despite the high effort, the causal relation between COVID-19 and GBS remains controversial. Case-control studies with high number of patients are needed to understand the relation between GBS and COVID-19

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