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Yıl:2010; Cilt: 23; Sayı: 1>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2010;23(1):32-37
Panik bozukluğu hastalarında sosyodemografik özellikler ve komorbidite
S Saygılı, O Karamustafalıoğlu
Vakıf Gureba Eğitim ve Araştırma Hastanesi
Amaç: Bu çalışmanın amacı, panik bozukluğu (PB) hastalarında sosyodemografik özellikleri ve eşlik eden Eksen I tanıların sıklığını araştırmaktır.

Yöntem: Çalışmaya, Vakıf Gureba Eğitim Araştırma Hastanesi ve Şişli Etfal Eğitim Araştırma Hastanesi psikiyatri polikliniklerine başvuran ve DSM-IV tanı ölçütlerine göre panik bozukluğu tanısı alan 77 hasta dahil edilmiştir. Eşlik eden psikiyatrik tanılar SCID-I (DSM-IV Eksen I Bozuklukları için Yapılandırılmış Klinik Görüşme) ile değerlendirilmiştir.

Bulgular: Hastaların 56'sı (%72.7) kadın, 21'i (%27.3) erkekti. Ortalama yaş 35.53±12.25 idi. Hastaların %37.7'si nin aile öyküsünde Eksen I psikiyatrik bozukluk tanısı olduğu görüldü. Hastaların %93'ü nde panik bozukluğun yanında, psikiyatrik bir eştanı saptandı. En sık saptanan eştanı ise majör depresyon (%47.2) idi.

Tartışma: Literatürdeki diğer çalışmalarla kıyaslandığında, kadın hasta sayısının fazla olmakla birlikte, kadın/erkek oranının daha düşük olduğu belirlenmiştir. Majör depresyon eştanı oranı literatürle uyumlu iken, yaygın anksiyete bozukluğu (YAB) ve sosyal anksiyete bozukluğu (SAB) eştanı oranlarının düşük olduğu saptanmıştır. Agorafobisi bulunan PB hastalarındaki SAB birlikteliği, agorafobisi bulunmayan PB grubuna göre anlamlı derecede daha yüksek bulunmuştur.

Sonuç: PB hastalarının yaklaşık yarısında majör depresyon görülürken, agorafobinin eşlik ettiği hastalarda eştanı sıklığının, özellikle de SAB sıklığının arttığı saptanmıştır.
Sociodemographic characteristics and comorbidity in panic disorder patients
Aim: The aim of the present study is to investigate the sociodemographic characteristics and the frequency of comorbid Axis I diagnosis in panic disorder (PD) patients.

Method: 77 patients who referrred to the psychiatry outpatient clinic of Vakif Gureba Training and Research Hospital and Sisli Etfal Training and Research Hospital and who were diagnosed with panic disorder according to DSM-IV diagnostic criteria were included in the study. Comorbid psychiatric diagnoses were evaluated by SCID-I (Structured Clinical Interview for DSM-IV Axis I Disorders).

Results: Fifty six of the patients (72.7%) were female, and 21 (27.3%) were male. Mean age was 35.53±12.25. Among patients, 37.7% had Axis I psychiatric disorder diagnosis in their family histories. In 93% of the patients, a psychiatric comorbidity was diagnosed along with panic disorder. The most common Axis I comorbidity was major depression (47.2%).

Discussion: Although the number of female patients was higher when compared to other studies, female/male ratio was determined to be lower. The rate of major depression was compatible with the literature, while comorbidity rates for generalized anxiety disorder and social anxiety disorder (SAD) were found to be lower than the groups in similar literature. SAD comorbidity rate in PD patients with agoraphobia was found to be significantly higher than the PD group without agoraphobia.

Conclusion: Nearly half of the PD patients had major depression, while in patients with comorbid agoraphobia, prevalence of comorbid disorders, particularly of SAD, was shown to increase.

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