Dergi Ara >>
Yıl:2009; Cilt: 3; Sayı: 1-2>> Özet
TAM METİN
Psikiyatride Derlemeler, Olgular ve Varsayımlar (RCHP); 2009;3(1-2):7-20
Agmatinin Nöropsikiyatrideki Yeri ve Önemi
F Arıcıoğlu
Marmara Üniversitesi, Eczacılık Fakültesi
Yeni bir nörotransmitter olduğu düşünülen agmatinin, çok çeşitli reseptörlerle etkileşerek antikonvülsan, nöroprotektif, analjezik ve antiiflamatuar bir madde olabileceği düşünülmektedir. Ayrıca, öğrenme ve bellek,
morfin bağımlılığı, şizofreni, stres, anksiyete ve depresyonda önemli rol oynamaktadır. Bir çok nörofizyolojik ve
patolojik olayda rol alan bu maddenin terapötik değeri olabileceği düşünülmektedir.
Relevance of Agmatine to Neuropsychiatry
Agmatine, a novel neurotransmitter, interacts with variety of receptors and has been implicated as an
anticonvulsant, neuroprotective, analgesic and antiinflammatory agent. Besides, It has an important role in
learning and memory, morphine dependence, schizophrenia, stres, anxiety and depression. Taken together, that
agmatine appear to be involved in a multiple of neurophysiological and pathological functions, pointed to the
potential therapeutic value of this agent.

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