Dergi Ara >>
Yıl:2006; Cilt: 19; Sayı: 3>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2006;19(3):155-161
Gitelman Sendromu ve Şizofreninin Birlikte Görüldüğü Bir Olgu
H Gümüş, C İlnem, F Yener
Bakırköy Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi 7. Psikiyatri Birimi
Bu yazıda Gitelman sendromu birlikteliği olan 28 yaşında bir şizofreni hastası sunulmuş ve ayırıcı tanısı tartışıl­mıştır. Gitelman sendromu, hipokalemik metabolik alkaloz, hipokahiüri ve hipomagnezemi İle karakterize otozo-mal resesif geçişli bir hastalık olarak tanımlanır. Birbirine benzer klinik tablolar olan Gitelman sendromu ve Bartter sendromu arasındaki farklılıklar da tartışılmaktadır. Bartter sendromu genellikle beş yaş altı hastaları etkilerken Gitelman sendromu tipik olarak daha geç yaşlarda ortaya çıkar. Aynı zamanda Gitelman sendromun-da hipokahiüri, hipomagnezemi ve normal idrar prostaglandin düzeyleri görülmektedir.
Klinisyen psikotik bozukluk hakkında karar vermeden önce Genel Tıbbi Durumu değerlendirmelidir. Psikotik bo­zukluk ve Genel Tıbbi Durum arasındaki ilişki için özgün bir kılavuz olmasa da en azından bazı genel prensipler yol gösterici olabilir. Bunlar; Genel Tıbbi Durum ile psikotik bozukluğun başlaması, alevlenmesi ve remisyonu arasında geçici bir ilişki olması ve Primer Psikotik Bozukluğun atipik semptomlarıdır. Burada Gitelman sendromuna eşlik eden psikotik bir bozukluk üzerinden bu ilişki tartışılmaktadır.
Comorbid Gitelman Syndrome and Schizophrenia: A Case Report
In this report, a 28 [year] old schizophrenic patient who had Gitelman syndrome comorbidity is presented and the differential diagnosis is discussed. Gitelman syndrome is, defined as an autosomal recessive disorder featuring hypokalemic metabolic alkalosis, hypocalciuria and hypomagnesemia. Differences between Gitelman syndrome and Bartter syndrome, a similar cinical entity, is also discussed. Bartter syndrome usually affect patients under the age of 5, while Gitelman syndrome patients typically present at older ages. Gitelman syndrome also includes hypocalciuria, hypomagnesemia and normal urine prostaglandin.
The clinician must evaluate the general medical condition before making any decision about the psychotic disor­der. There is no spesific guide for the relationship between a psychotic disorder and general medical condition but at least some general principles could guide us. These are temporary relationship between onset, course or the remission of the psychotic disorder atul the medical condition; and, atypical symptoms of the primary psycho­tic disorder. Here we discussed this relationship between psychotic disorder and Gitelman syndrome.

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