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Yıl:2024; Cilt: 61; Sayı: 2>> Özet
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Nöropsikiyatri Arşivi; 2024;61(2):135-140
Psikiyatri Hastalarında Elektrokonvülsif TedavininFrontal QRS-T Açısı Üzerindeki Etkis
Ü Atılan-Fedai, H Fedai
Harran Üniversitesi, Şanlıurfa
Amaç: Elektrokonvülsif tedavi (EKT) iyi tolere edilen ve komplikasyon riski düşük olan biyolojik tedavilerden biridir. EKT’ye bağlı ventriküler aritmi, miyokard enfarktüsü ve kardiyak arrest gibi akut kardiyovasküler komplikasyonlar kaydedilmiştir. Artmış frontal QRS-T (fQRS-T) açısı ventriküler aritmi, ani kardiyak ölüm ve toplam mortalite ile ilişkilendirilmiştir. Bu çalışmada, EKT’nin miyokard üzerindeki etkisini fQRS-T açısı, QRS süresi, QT ve QTc aralığı gibi elektrokardiyografi (EKG) parametrelerini kullanarak değerlendirmeyi amaçladık. Yöntem: Bu çalışmaya bipolar bozukluk (n=36), depresif bozukluk (n=70) ve şizofreni (n=2) tanılarıyla EKT uygulanan toplam 108 hasta dâhil edildi. Tüm hastaların EKT öncesi, EKT’den 15 dakika sonra ve EKT’den 24 saat sonra 12 derivasyonlu yüzey EKG’leri alındı. Bulgular: QRS süresi, QT intervali ve düzeltilmiş QT (QTc) intervali takip süresince anlamlı olarak değişmedi. Ancak, EKT’den 15 dakika sonra fQRS-T açısının başlangıç açısına göre anlamlı olarak arttığı saptandı. (p<0,001). Ayrıca EKT’den 15 dakika sonra fQRS-T açısındaki bu artışın EKT’den 24 saat sonra anlamlı olarak azaldığını tespit edildi (p=0,031). Başlangıç ve 24. saat fQRS-T açısı arasında anlamlı bir fark yoktu (p=0,154). Sonuç: Çalışmamızda EKT’den 15 dakika sonra fQRS-T açısında anlamlı bir artış gözlenmiştir. fQRS-T açısının 24 saat sonra normale döndüğü tespit edilmiştir.. Bulgularımız EKT’nin fQRS-T açısına göre kardiyovasküler olay riski üzerinde kalıcı bir yan etkisi olmadığını gösterebilir.
The Effect of Electroconvulsive Therapy on Frontal QRS-T Angle inPsychiatric Patients
Introduction: Electroconvulsive therapy (ECT) is one of the biological therapies that is well tolerated and has a low risk of complications. Acute cardiovascular complications related to ECT such as ventricular arrhythmia, myocardial infarction and cardiac arrest have been recorded. Increased frontal QRS-T (fQRS-T) angle was associated with ventricular arrhythmia, sudden cardiac death and total mortality. In this study, we aimed to evaluate the effect of ECT on the myocardium using electrocardiography (ECG) parameters such as fQRS-T angle, QRS duration, QT and QTc interval. Methods: A total of 108 patients diagnosed with bipolar disorder (n=36), depressive disorder (n=70) and schizophrenia (n=2) who underwent ECT were included in this study. 12-lead surface ECG of all patients were taken before the ECT, 15 min. after ECT and 24 hour after ECT. Results: QRS duration, QT interval and corrected QT (QTc) interval were not changed significantly during the follow-up period. However, we found that, fQRS-T angle was significantly increased 15 minutes after ECT compared to baseline angle (p<0.001). We also detected that this increase in fQRS-T angle 15 minutes after ECT was significantly reduced 24 hours after ECT (p=0.031). Meanwhile, there was no significant difference between baseline and 24th hour fQRS-T angle (p=0.154). Conclusions: In our study, a significant increase in fQRS-T angle was observed 15 min after ECT. However, the fQRS-T angle was found to return to normal after 24 hours. Our findings may indicate that ECT does not have a permanent side effect on the risk of cardiovascular events according to the fQRS-T angle.

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