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Yıl:2024; Cilt: 61; Sayı: 2>> Özet
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Nöropsikiyatri Arşivi; 2024;61(2):107-112
Kronik Şizofrenide Yineleyici Transkranial Manyetik Stimülasyonun Belirtiler,Biliş ve Öznel Yaşantılar Üzerine Etkisi: Kontrollü Çalışma
L Liu, L Shi, D Xu, X Wang, Y Wang, Q Wang, X Wang
Hebei General Hospital for Veterans Affiliated to North China University, Baoding City/China
Amaç: Bu çalışmada yüksek frekanslı yineleyici transkranial manyetik stimülasyonun (rTMS) kronik şizofreni hastalarında belirtiler, bilişsel işlevler ve öznel deneyimler üzerindeki etkilerini incelemek ve TMS yönteminin genel anlayışını artırmak amaçlanmaktadır. Yöntem: Çalışmaya kronik şizofreni tanısı olan 33 hasta dâhil edildi. 17 hastaya rTMS uygulanırken, 16’sı kontrol (sham) grubuna alındı. Pozitif ve Negatif Sendrom Ölçeği, Tekrarlanabilir Nörolopsikolojik Durum Ölçeği, İçgörü ve Tedavi Tutumu Anketi ve TMS sonrası deneyimlerini değerlendirmek için araştırmacılar tarafından geliştirilen bir özbildirime dayalı yaşantı kontrol listesi tüm hastalara uygulandı. Bulgular: Belirtiler, bilişsel işlevler ve içgörü açısından gruplar arasında istatistiksel farklılık yoktu. Ancak rTMS grubu genel olarak daha iyi bir tedavi deneyimi ve daha olumlu öznel yaşantılar bildirdi. Sonuç: rTMS tedavisi, belirtilerde, bilişsel işlevlerde ve içgörüde herhangi bir iyileşmeye neden olmazken, daha olumlu öznel yaşantılar ile sonuçlandı, bu da tedaviye uyumu iyileştirebilir.
High-Frequency Repetitive Transcranial Magnetic Stimulation andIts Effects on Symptoms, Cognition and Subjective Experiences inChronic Schizophrenia: A Sham-Controlled Study
Introduction: Our object is to examine the effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) on the symptoms, cognitive functions and subjective experiences in patients with chronic schizophrenia and to enhance the overall understanding of the TMS method. Methods: Thirty three patients who had chronic schizophrenia were included in the study. Seventeen patients received rTMS and 16 received sham. The Positive and Negative Syndrome Scale, Repeatable Battery for the Assessment of Neuropsychological Status Scale, Insight and Treatment Attitudes Questionnaire and a self-experience checklist developed by the researchers to evaluate post-TMS experiences were applied to all patients. Results: There were no statistical differences between the groups with regard to symptoms, cognitive functions and insight. However rTMS group reported overall better treatment experience and more positive subjective experiences. Conclusion: rTMS treatment did not cause any improvement in symptoms, cognitive functions and insight but provided a better self- experience, which might improve treatment compliance.

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