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Yıl:2022; Cilt: 25; Sayı: 4>> Özet
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Klinik Psikiyatri Dergisi; 2022;25(4):434-440
Erişkinlik döneminde streptokok enfeksiyonu ile ilişkili pediyatrik otoimmün nöropsikiyatrik bozukluk(PANDAS) tanısı düşündüren bir olgu
S Aydın, AE Savaş, EA Aslan, S Batmaz
Gaziosmanpaşa Üniversitesi, Tokat
Streptokok enfeksiyonuyla ilişkili pediyatrik otoimmün nöropsikiyatrik bozukluklar (PANDAS) A grubu-beta hemolitik streptokok enfeksiyonu sonrası otoimmün tepkinin bir sonucu olarak ortaya çıkan, çocukluk çağında obsesif kompülsif belirtiler ve tikler bulunan tabloyu tanımlamaktadır. Çocukluk çağında çeşitli semptomlarla seyreden, kliniği karışık olan, bu nedenle tanı koymanın zor olduğu PANDAS erken saptanarak enfeksiyon tedavisinin sağlanması ile nöropsikiyatrik semptomlarda belirgin gerileme izlenen bir sendromdur. Bu yazıda, sık tekrarlayan üst solunum yolu enfeksiyonlarıyla obsesif kompulsif bozukluk (OKB)bulguları ve tikleri alevlenen ve pediyatrik otoimmün nöropsikiyatrik bozukluk (PANDAS) tanısını düşündüren 21 yaşında bir olgu sunulmuştur. Tanı almamış ve tedavi edilmemiş PANDAS kronisite kazanarak ömür boyu obsesif kompülsif bozukluk ve tik bozukluğuna dönüşme açısından yüksek risklidir. PANDAS tanısı olduğu düşünülen olgular zaman geçirmeden uygun merkeze yönlendirilerek tedavi başlanmalıdır.
An adult case suggestive of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) diagnosis
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) describe a picture with obsessive-compulsive symptoms and tics in childhood as a result of autoimmune response after group A-beta hemolytic streptococcal infection. PANDAS is a syndrome which progresses with various symptoms in childhood and is difficult to diagnose, and in which a significant regression in neuropsychiatric symptoms is observed with early detection and treatment of infection. In this article, a 21-year-old case with OCD findings and tics exacerbated by recurrent infections, suggesting the diagnosis of PANDAS is presented. Undiagnosed and untreated PANDAS has a high risk of becoming chronic and transforming into lifelong obsessive compulsive disorder and tic disorder. Patients who are thought to have a diagnosis of PANDAS should be referred to the appropriate center without delay and treatment should be started.

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