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Yıl:2017; Cilt: 4; Sayı: 2>> Özet
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Türk Uyku Tıbbı Dergisi; 2017;4(2):43-47
Obstrüktif Uyku Apne Sendromu, Kronik Obstrüktif Akciğer Hastalığı ve Astım Birlikteliği
S Saraç, GÇ Afşar
Sağlık Bilimleri Üniversitesi, İstanbul
Amaç: Uyku bozuklukları, kronik havayolu hastalıkları ile sıklıkla birlikte bulunan hem hastalığın gidişatını hem de kişinin hayat kalitesini etkileyen durumlardır. Obstrüktif uyku apne sendromu (OUAS) ise uykuda solunum bozukluklarının en sık rastlanılan grubudur. Çalışmamızda retrospektif olarak uyku kliniğimizde yatarak polisomnografik tetkik yapılmış ve OUAS tanısı almış hastalarda astım ve kronik obstrüktif akciğer hastalığı (KOAH) sıklığını; bu hastalıkların OUAS şiddetine etkisini araştırmayı hedefledik. Gereç ve Yöntem: Hastaların yaş, cinsiyet, vücut kitle indeksi (VKİ), spirometri değerleri, Epworth Uykululuk skalası (EUS) ve polisomnografik bulgularını kaydettik. Bulgular: Çalışmaya 970 OUAS’lı hasta alındı. Hastalar 3 gruba ayrıldı: Yalnız OUAS (%86,8), OUAS+KOAH (%7,6), OUAS+astım (%5,6) idi. KOAH ve astım sıklığı normal popülasyona göre fazla değildi. OUAS ve KOAH birlikteliği olan grupta erkek cinsiyet (p=0,001), ileri yaş (p=0,001), sigara içiciliği (p=0,001), EUS (p=0,04) belirgin şekilde fazla idi. Polisomnografi bulgularından minumum oksijen satürasyonu, yalnız OUAS olan gruba göre düşüktü (p=0,004). OUAS ve astım birlikteliği olan grupta kadın cinsiyet ile VKİ daha fazla idi (p=0,001). Polisomnografi bulgularından minumum oksijen satürasyonu sadece OUAS olan gruba göre düşük idi (p=0,04). Sonuç: KOAH ve astım varlığı OUAS’ı olumsuz yönde etkileyebilir. Erkek cinsiyet, sigara içiciliği, ileri yaş gibi durumlarda KOAH açısından; kadın cinsiyet, orta yaş, atopi varlığı gibi durumlarda astım açısından ileri tetkik yapılabilir.
Comorbidity of Obstructive Sleep Apnea Syndrome, Chronic Obstructive Lung Disease and Asthma Chronic Airway Diseases and Sleep Apnea
Objective: Sleep disorders are conditions that often interfere with chronic airway diseases and affecting both the course of illness and the quality of life. Obstructive sleep apnea syndrome (OSAS) is the most common group of sleep-disordered breathing. We aimed to investigate the prevalence of asthma and chronic obstructive pulmonary disease (COPD) on OSAS severity in patients who were retrospectively examined by polysomnographic examination in our sleep clinic and who were diagnosed with OSAS. Materials and Methods: We recorded the age, sex, body mass index (BMI), spirometry values, Epworth sleepiness scale (ESS) and polysomnographic findings of the patients. Results: Nine hundred seventy patients with OSAS were included in the study. Patients were divided into 3 groups: only OSAS (86.8%), OSAS with COPD (7.6%) and OSAS with asthma (5.6%). The frequency of COPD and asthma was not higher than in the normal population. The male gender (p=0.001), older age (p=0.001), ESS (p=0.04) and smoking status (p=0.001) were significantly higher in the group with OSAS and COPD. The minimum oxygen saturation which is polysomnography finding was lower than only OSAS group (p=0.004). In the OSAS and asthma association group, female gender and BMI were higher (p=0.001). The polysomnography findings showed that the minimum oxygen saturation was lower than only OSAS group (p=0.04). Conclusion: The presence of COPD and asthma can affect OSAS in negative way. Male gender, smoking status, older age in terms of COPD; female gender, middle age and presence of atopy, further examination can be done in terms of asthma.

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