Dergi Ara >>
Yıl:1996; Cilt: 7; Sayı: 4>> Özet
Türk Psikiyatri Dergisi; 1996;7(4):257-265
Majör Depresyon, Anksiyete Bozukluğu ve Eştanılı Durumlarda Ayrışan ve Örtüşen Özellikler-l : Klinik BelirtilerYönünden Karşılaştırmalı Bir Çalışma
L KÜEY. Ö AYDEMİR, Ş GÜLSEREN, S KÜLTÜR
Kapsamlı bir araştırmanın parçası olan bu çalışmada, depresyon, anksiyete ve eştanılı durumların ayrışan ve/veya örtüşen klinik özelliklerinin fenomenolojik düzeyde karşılaştırılması amaçlanmıştır. Araştırma eğitim hastanesi niteliğindeki bir psikiyatri kliniğine başvuran ve yatarak ya da ayaktan sağaltılan hastalardan ardışık belirlenen ve DSM-III-R’ye göre major depresyon (s: 31), anksiyete bozukluğu (s: 20) ya da her ikisinin birlikte olduğu eştanılı durum (s: 11) tanısı alanlar üzerinde yürütülmüştür. Bozukluk şiddeti Klinik Global İzlenim (KGİ), belirti örüntüsü ise Hamilton Depresyonu Değerlendirme Ölçeği (HDDÖ) ve Hamilton Anksiyeteyi Değerlendirme Ölçeği (HADÖ) ile değerlendirilmiştir. Başvuru yaşı ve ilk hastalanma yaşı yönünden anksiyete bozukluğu grubunun anlamlı düzeyde düşük ortalamalara sahip olduğu görüldü. Anksiyete sendromu şiddeti yönünden tanı grupları arasında farklılık saptanmazken, depresif sendrom şiddeti anksiyete bozukluğu grubunda diğer iki gruba göre anlamlı düzeyde düşük bulundu. Ayırt edici belirtiler incelendiğinde, anksiyete bozukluğu grubu için “gerilim duygusu”, major depresyon grubu için “psikomotor yavaşlama”, eştanılı grup için ise “depresif mizaç” ve “zayıflama” belirlendi. Grupların örtüşmesinin yönünün anksiyete bozukluğundan major depresyon ve eştanılı durumlara doğru olduğu; ayrışmayı sağlayan belirtilerin ise depresyon belirtileri olduğu görüldü. Ayrıca major depresyon grubunun, şiddet olarak eştanılı ya da anksiyete bozukluğu grubu düzeyinde anksiyete sendromu barındırması dikkat çekmekteydi.
Distinctive and Overlapping Features of Patients with Major Depression, Anxiety Disorders and Comorbid States-1: A Comparative Study in Terms of Cilinical Symptomatology
As a part of a comprehensive research, this study aimed to investigate the overlapping and distinctive clinical features of major depression, anxiety disorders and comorbid states on a phenomenological level. Patients diagnosed by Structured Clinical Interview for DSM-III-R (SCID) as having either major depression (n= 31), anxiety disorder (n = 20) or comorbid states (n= 11) were included in the study and symptomatology were assessed by Hamilton Rating scale for depression (HRSD) and Hamilton Anxiety Rating Scale (HARS) and clinical severity by Clinical Global Impression (CGI). Anxiety disorder group had significantly lower means of age at admission and age of onset. There was no difference between the groups of patients in terms of level of anxiety syndrome but the level of depression syndrome was significantly lower in the anxiety disorder group than in the other two groups. “Feelings of tension” was discriminating the anxiety disorder group; “psychomotor retardation” was discriminating the major depression group; and “depressive mood” and “weight loss” were discriminating the comorbidity group. The direction of the overlap was from the anxiety disorder towards major depression and comorbid states while the distinctive features were determined by the depressive symptoms. In addition, the major depression group had a level of anxiety syndrome as severe as the anxiety disorder group and the comorbid group.

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