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Yıl:2015; Cilt: 2; Sayı: 2>> Özet
TAM METİN
The Journal of Neurobehavioral Sciences; 2015;2(2):83-84
Sertralinin İndüklediği Normoprolaktinemik Galaktore
MA Camkurt, N Şimşek
Afşin Devlet Hastanesi, Kahramanmaraş
Galaktore psikiyatri pratiğinde sıklıkla tipik antipsikotiklerin bir yan etkisi olarak ortaya çıkmaktadır. Öte yandan imipraminin antidepresan olarak kullanılmaya başlanmasından beri, antidepresanlara bağlı da galaktore gelişebileceği bildirilmiştir. Galaktore klinikte sıklıkla artmış prolaktin düzeyleri ile karşımıza çıkmakla beraber bazı durumlarda prolaktin düzeyleri normalken de gelişebilmektedir. Bu güne kadar sertralinle ilgili 2 tane prolaktin düzeyleri normal sınırlarda iken gelişen galaktore olgusu bildirilmiştir. Bu vakamızda sertralin 50 mg/gün başlandıktan 1 ay sonra gelişen galaktore olgusunu sunmayı amaçladık.
Sertralin Induced Normoprolactinemic Galactorrhea
Galactorrhea is defined as non-puerperal lactation and frequently occurs as an adverse drug reaction due to typical antipsychotics. Furthermore, antidepressants, especially SSRIs, cause galactorrhea since the introduction of imipramine to psychiatry practice. Although galactorrhea usually accompanies increased prolactin levels, in some cases prolactin levels could be within the normal range. To date there are two case reports of normoprolactinemic galactorrhea due to sertraline and here we report a patient who developed normoprolactinemic galactorrhea 1 month after initiating sertraline 50 mg/day.

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