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Yıl:2014; Cilt: 1; Sayı: 3>> Özet
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Türk Uyku Tıbbı Dergisi; 2014;1(3):66-70
Obstrüktif Uyku Apne Tedavisinde Otomatik BPAP Cihazının Klinik Yararlılığı
N Altıntaş, B Oktay, H Fırat, P Strollo
Namık Kemal Üniversitesi, Tekirdağ
Giriş: CPAP’ı tolere edemeyen tıkayıcı uyku apne hastalarında BPAP, CPAP’ın etkin bir alternatifidir. BPAP Auto® with BiFlex™ (BPAPauto) cihazı son zamanlarda geliştirilen bir otomatik titrasyon özelliği olan BPAP’dır. Bu çalışmanın amacı bu yeni cihazın etkinliğini laboratuvar ortamında yapılan polisomnografi (PSG) ile değerlendirmektir. Gereç ve Yöntem: Bu çalışma prospektif vaka-kontrol çalışmasıdır. Hale hazırda BPAP veya CPAP cihazı kullanan obstrüktif uyku apneli hastalar çalışmaya alındı ve BPAPauto cihazı ile laboratuar ortamında PSG yapıldı. Bulgular: Çalışma kriterlerini karşılayan 27 hasta çalışmaya alındı. Tüm çalışmaya alınan hastalara laboratuvar ortamında yapılan PSG eşliğinde BPAPauto tedavisi verildi. Uyku ve solunum parametreleri incelendi. Ortalama apne-hipoapne indeksi 2,2±2,5 olay/saat olarak bulundu. SaO2 (oksijen saturasyonu) %94,0±1,8 bulundu. Solunum olaylarının düzeltmek için gereken ortalama inspiratuvar pozitif hava yolu basıncı (IPAP) 14,1±3,4 cmH2O ve ortalama ekspiratuvar pozitif hava yolu basıncı (EPAP) 10,7±3,9 cmH2O bulundu. Sonuç: BPAPauto uyku kalitesini bozmaksızın, uygun BPAP basınçlarını ayarlayabilmekte ve oksijen saturasyonunu kontrol altında tutabilmektedir. Obstrüktif uyku apnenin tedavisinde BPAPauto’nun avantajlarının ve potansiyel rollerinin incelene bilmesi için daha ileri randomize kontrollü çalışmalara ihtiyaç vardır.
Clinical Feasibility of an Auto-Adjusting Bi-Level PAP Device for the Treatment of Obstructive Sleep Apnea
Introduction: Bi-Level positive airway pressure (BPAP) is an effective alternative to continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) who could not tolerate CPAP. An automatically titrating BPAP device has recently been developed, BPAP Auto® with BiFlex™ (BPAPauto). The primary aim of this study was to examine the performance of this new device during attended polysomnography (PSG). Materials and Methods: This was a prospective case series study. Participants with OSA currently using CPAP or BPAP therapy were recruited and undergo in-lab PSG study with BPAPauto. Results: A total of 27 participants met the criteria, enrolled the study. All participants received BPAPauto therapy during an attended PSG. Sleep and respiratory data were examined. The mean apnea hypopnea index was found 2.2±2.5 events/hour. SaO2 (oxygen saturation) was 94.0%±1.8. The mean inspiratory positive airway pressure (IPAP) abolish respiratory events was 14.1±3.4 cmH2O and that of expiratory positive airway pressure (EPAP) was 10.7±3.9 cmH2O. Conclusions: BPAPauto is able to establish an appropriate Bi-Level PAP and control oxygen saturation without excessive disruption of sleep. Further studies using randomized control design are needed to examine potential roles and advantages of BPAPauto for treatment of OSA.

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