Dergi Ara >>
Yıl:2004; Cilt: 12; Sayı: Ek 2>> Özet
Psikiyatri Psikoloji Psikofarmakoloji (3P) Dergisi; 2004;12(Ek 2):63-70
Uyku bozukluklarının genetiği
O Çalıyurt
Trakya Üniversitesi Tıp Fakültesi Psikiyatri AD / EDİRNE
Uyku bozuklukları toplumda çok yaygın olarak görülen bozukluklardır. Uyku bozuklukları sonucunda ortaya çıkan sorunlar da bireysel ve toplumsal olumsuz sonuçları beraberinde getirmektedir. Uyku süresi, uyku kalitesi ve uykuda ortaya çıkan anormal durumlar gibi normal uykunun özellikleri ve çoğu uyku bozukluğu ailesel olarak geçiş göstermekte ve genetik olarak etkilenmektedir. Ayrıca uyku-uyanıklık döngüsünü belirleyen sirkadiyen ritimler de genetik kontrol altında bulunmaktadır. Özellikle son yıllarda yapılan araştırmalar ile uyku ve uyku bozukluklarının temelinde yer alan genetik özellikler belirlenmektedir. Bu sonuçlar ile de uykuyu ve bozukluklarını daha iyi anlamamız, yatkın ailelerde sorunları önceden saptamamız, tedavi sürecinde genetik yaklaşımları kullanmamız mümkün olabilecektir. Diğer yandan psikiyatrik bozukluklarda çok sık görülen uyku bozukluklarının genetik yönlerinin açığa kavuşması ile psikiyatrik bozuklukların genetiğini anlamamıza da ışık tutabilecektir.
Genetics of sleep disorders
Sleep disorders are very prevalent in the society. Consequences of these disorders are related with the individual and social negative impacts. Normal features of the sleep, such as sleep duration, sleep quality and abnormal events during the sleep, and most of the sleep disorders are substantially influenced by genetic factors. Furthermore, circadian rhythms that they play an important role on sleep-wake organisation, are under control of the genetic factors. With the recent studies genetics of the sleep disorders are being explored. These results lets us to understand sleep disorders, detect sleep disorders in families and detect sleep disorders before came out, and use genetic approach for treatment of sleep disorders. On the other hand, sleep disorders are frequent comorbide condition seen in psychiatric disorders and genetics of sleep disorders could help us to understand the psychiatric genetics.

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