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Yıl:2014; Cilt: 25; Sayı: 1>> Özet
Türk Psikiyatri Dergisi; 2014;25(1):1-8
Bipolar Bozukluk ve Erişkin Dikkat Eksikliği Hiperaktivite Bozukluğunun Nöropsikolojik Açıdan Karşılaştırılması
N Levent, S Tümkaya, F Ateşçi, H Tüysüzoğlu, G Varma, N Oğuzhanoğlu
Kumluca Devlet Hastanesi, Antalya
Amaç: Bu çalışmada bipolar bozukluk ve erişkin dikkat eksikliği hiperaktivite bozukluğu (DEHB) hastalarının bilişsel işlevlerinin karşılaştırılması amaçlanmıştır. Yöntem: Çalışmaya 66 bipolar bozukluk tanılı hasta, 63 DEHB tanılı hasta ve 58 sağlıklı kontrol olgusu alındı. Tüm katılımcılara DSM-IV Eksen-I Bozuklukları için Yapılandırılmış Klinik Görüşme (SCID-I), Wender Utah Derecelendirme Ölçeği, Erişkin Dikkat Eksikliği Hiperaktivite Derecelendirme Ölçeği uygulanırken, bipolar bozukluk grubuna bunlara ek olarak Hamilton Depresyonu Derecelendirme Ölçeği ve Young Mani Derecelendirme Ölçeği uygulandı. Daha sonra tüm katılımcılar Sayı Dizisi Testi, Sözel Bellek Süreçleri Testi, Wisconsin Kart Eşleme Testi ve Stroop Testi’ni içeren bir grup nöropsikolojik test ile değerlendirildiler. Bulgular: Bipolar bozukluk, DEHB ve kontrol grupları yaş, cinsiyet ve eğitim süresi açısından birbirlerinden anlamlı farklılık göstermiyorlardı. Bipolar hastalar Sayı Dizisi Testi, Sözel Bellek Süreçleri Testi, Wisconsin Kart Eşleme Testi ve Stroop Testi’nde kontrol grubuna göre daha kötü performans gösterdiler. DEHB’li hastalar ise Stroop Testi’nde (süre farkı alt testi) kontrollerden kötüydüler. Bipolar bozukluk hastaları Stroop Testi dışındaki nöropsikolojik testlerde DEHB grubundan daha kötüydüler. Sonuç: Genel olarak bipolar bozukluk hastaları sözel bellek ve yönetici işlevler açısından erişkin DEHB hastalarından daha şiddetli bilişsel bozukluklar göstermektedir. Bu bulgular en azından bilişsel açıdan bipolar bozukluk ve DEHB’nin birbirinden farklı bozukluklar olduğu düşüncesini desteklemektedir.
A Neuropsychological Comparison of Bipolar Disorder and Adult Attention Deficit Hyperactivity Disorder
Aim: The present study aimed to compare cognitive signs of bipolar disorder patients with that of adult attention-deficit/hyperactivity disorder (ADHD) patients. Method: The study comprised 66 bipolar disorder patients, 63 ADHD patients, and 58 healthy controls.Structured Clinical Interview for DSM-IV Axis-I Disorders (SCID-I), Wender Utah Rating Scale, and Adult Attention-Deficit/Hyperactivity Rating Scale were performed in all subjects, whereas bipolar disorder patients underwent additional Hamilton Depression Rating Scale and Young Mania Rating Scale. Subsequently, all participants underwent cognitive assessment including Digit Ordering Test, Verbal Memory Process Test, Wisconsin Card Sorting Test and Stroop Test. Results: Bipolar disorder, ADHD and control groups did not differ significantly from each other with regard to age, sex and duration of education. Bipolar patients displayed poorer performance in Digit Span Test, Verbal Memory Process Test, Wisconsin Card Sorting Test and Stroop Test as compared to the control group. ADHD patients were worse than the control subjects in Stroop Test (subtest of difference in times). Bipolar disorder patients were poorer than ADHD patients in cognitive tests except for Stroop Test. Conclusion: In general, bipolar disorder patients have much more severe cognitive impairment than ADHD patients in terms of verbal memory and executive functions. The results supports the idea of bipolar disorder and ADHD are different, at least in terms of cognitive performance.

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