Dergi Ara >>
Yıl:2012; Cilt: 25; Sayı: 1>> Özet
TAM METİN
Düşünen Adam: Psikiyatri ve Nörolojik Bilimler Dergisi; 2012;25(1):88-89
Metoklopramidle gelişen akut distoni: Bir olgu sunumu
S Korkmaz, M Atmaca, S Sağlam
Elazığ Ruh Sağlığı ve Hastalıkları Hastanesi, Elazığ
Distonide, altta yatan nörokimyasal patoloji bilinmemekle birlikte, bazal gangliyonlardaki dopaminerjik aktivitede
görülen anormalliklerin etkili olduğu üzerinde durulmaktadır. Çoğunlukla klasik antipsikotiklerle ortaya
çıkan bir yan etki olmakla birlikte, metaklopramid gibi dopaminerjik yolak üzerinde etkili olabilecek çeşitli ilaçların
alınmasıyla da ortaya çıkabilir. Çalışmamızda, terapötik dozda metoklopramid tedavisi almakta iken, akut
distonik reaksiyon gelişmesi nedeniyle polikliniğimize yönlendirilen 17 yaşında bir olgu sunulmuştur.
Acute dystonia associated with metoclopramide: a case presentation
Although the underlying neurochemical anomaly is not known, it has been implicated that the
pathophysiology of dystonia may be associated with abnormal dopaminergic activity in basal ganglia.
Although it is frequently seen with classical antipsychotics, some dopaminergic agents such as
metoclopramide may cause this side effect. In this paper, we present a 17 [year]s old woman under treatment
with metoclopramide in therapeutic doses, who was referred to our hospital because of acute dystonia.

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