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Yıl:2008; Cilt: 46; Sayı: 3>> Özet
TAM METİN
Yeni Symposium; 2008;46(3):130-136
Dikotik Dinleme Paradigması ile Beyin Asimetrisinin Elektrofizyolojik Değerlendirmesi
O Bayazıt, A Öniz, O Güntürkün, M Özgören
Dokuz Eylül Üniversitesi, Tıp Fakültesi, Biyofizik A.D., İzmir, Türkiye
Amaç: Beynin asimetrik sistemlerinden biri olan hecelerin algılanması asimetrisini, nonenvasif yöntem
olan dikotik dinleme testi altında çekilen EEG kaydı ile değerlendirebilmektir.
Yöntem: 20 sağlıklı gönüllü (ortalama 21.15 yaş) ile yapılan bu çalışmada elektrofizyolojik ölçümler
64 kanaldan yapılmış olup öncelikli olarak beş elektrot bölgesi (F3, F4, Cz, T7, T8) incelenmiştir.
İnceleme, sağ kulak tercihi durumunda oluşan ve 108–244 ms aralığında N100’ü içeren ilk cevap
kompleksi (C1: N1P2) genlik değerleri ölçülmüştür.
Bulgular ve Tartışma: Türk toplumunda, elektrofizyolojik incelemeleri de içerecek şekilde ilk kez
uygulanmış olan bu dikotik dinleme çalışmasının sonuçları davranışsal olarak ve kişilerin verdiği hatalı
cevaplar gözetilmeksizin değerlendirildiğinde, sağ kulak tercihi %57.1, sol kulak tercihi %35
olarak bulunmaktadır (P<0.001). Dikotik hece çiftlerinden bâzılarında diğerlerinden farklı olarak
kulak tercihi gözlenmektedir.
Yapılan analizler sonucunda, sağ kulak tercihi durumunda 108–244 ms aralığında ölçülen N100’ü
içeren ilk cevap kompleksi (C1: N1P2) genlik değeri en fazla Cz, bundan daha az olarak sırasıyla F4,
F3, T8 ve T7 elektrotlarında saptanmıştır.
Temporal bölgede, sağ ve sol beyin hemisferleri kıyaslandığında sağ bölgede gözlenen C1 cevapları
sol bölgelerde gözlenenlerden büyük olarak bulunmuştur (P<0.001). Santral bölge elektrodunda
(Cz) diğer elektrotlara göre daha büyük genlik değerleri (15.5 μV) gözlenmiştir (P<0.05). Bu durum
Cz ölçüm bölgesinin her iki hemisferdeki ses algılama bölgesinin kavşak noktasında bulunması
ndan kaynaklanıyor olabilir.
Sonuç: Çalışmada elde edilen ön bulgular ışığında, Türk toplumunda da dikotik dinleme paradigmasının elektrofizyolojik adaptasyonun kolay uygulanır ve etkin bir yöntem olarak beynin işitsel
sistem asimetrisini yansıtabilecek bir uygulama olduğu ileri sürülmektedir.
Electrophysiological Assessment of Brain Asymmetry Using a Dichotic Listening Paradigm
Objective: In this study, a non-invasive dichotic listening paradigm was used during EEG recording
in order to evaluate one of the asymmetrical brain functions, the perception of syllables.
Method: Twenty healthy volunteers (mean age 21.15 [year]s) were recruited in the study. The EEG
measurements were performed on 64 channels, five of which were primarily subgrouped for the
analysis (F3, F4, Cz, T7, T8).
Results and Discussion: This procedure, incorporating the electrophysiological assessment, as the
first known study in Turkish population, has revealed 57.1% right ear advantage and 35% left ear
advantage (not considering the incorrect responses) (P<0.001). Some of the dichotic pairs resulted
in a different distribution upon comparison within individual syllable-pairs.
The analysis in the right-ear advantage group, in the time window of 108-244 ms, revealed highest
N100 response complexes (C1:N1P2) at the central (Cz) electrode, followed by F4, F3, T8 and T7 responses. The comparison of C1 responses in temporal regions across the hemispheres, showed right
dominance (P<0.001). The central (Cz) response reaching 15.5 μV, can be explained by the presence
of this electrode site over a possible functional junction area of sound perception in two hemispheres
Conclusion: The results of this study point to the applicability and effectiveness of using a modified
electrophysiological dichotic listening paradigm, also in the Turkish population, with a possible
future application in assessing the functional asymmetry of brain functions.

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