Dergi Ara >>
Yıl:2007; Cilt: 1; Sayı: 2>> Özet
TAM METİN
Psikiyatride Derlemeler, Olgular ve Varsayımlar (RCHP); 2007;1(2):39-46
Şizofrenide Yürütücü İşlevler
A Karaoğlan, A Akdemir
MKÜ Tayfur Ata Sökmen Tıp Fak. Psikiyatri AD
Şizofrenide bilişsel işlevlerin bozukluğuna dair oldukça geniş bir literatür bulunmaktadır. Bilişsel bozulma hastalığın ilk atağından itibaren saptanmış olup, hastalığın kronik evrelerine kadar devam ettiğinin kanıtları vardır. Özellikle bellek ve yürütücü işlevlerin hastalık başlangıcında bozuk olduğunu gösteren çalışmalar, literatürde yer almaktadır. Bu bozuklukların ilaç etkisi ile olmadığını destekler biçimde, ilk ataktaki ilaçsız hastalarda gösterildiği çalışmaların yanı sıra, belirtiler, cin­siyet ve hastalık süresi gibi etkenlerle ilişkisini araştıran çalışmalar da mevcuttur. Bu yazıda şizofreni hastalarının günlük yaşam becerilerini ve tedavi süreçlerini doğrudan etkileyebilecek yürütücü işlev değişiklikleri ve ilişkili faktörler gözden geçirilmiştir.
Executive Functions in Schizophrenia
There is a substantial literature about cognitive dysfunctions of people with schizophrenia. Cognitive dysfunctions were reported both in the first episode and longitudinal course of schizophrenia. Studies designed for excluding drug effects reported cognitive dysfunction across drug-naive, first episode schizophrenic patients. Studies examining the effect of factors such as symptomatology, sex, and duration of illness are also present. In this paper alterations of executive functions that may affect the daily activities of patients with schizophrenia and the probable related factors are reviewed.

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