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Yıl:1991; Cilt: 1; Sayı: 2>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 1991;1(2):11-16
Şizofrenide Görüntüleme Teknikleri
S Saygılı, H Kara
Bakırköy Ruh ve Sinir Hast. Hastanesi, İstanbul
Bilgisayarlı Beyin Tomografisi gibi beyinde yapısal değişiklikleri değerlendirme imkanı veren yeni teknolojilerin gelişmesi, araştırmaya alınan hasta ve kontrol gruplarının bûyük gruplar halinde ayrıntılı biçimde incelenmesine olanak tanımıştır. Johnstone 100 şizofrenik hastaya ilişkin BBT bulgularını yayınlayan ilk arastırıcı olmuştur. Johnstone'un bu çalışmasında yaşlı hastaların (şizofren) kontrollere göre daha geniş lateral ventriküllere sahip olduğu bildirilmiştir. Son 15 yıldır lateral ventrikül genişliği şizofrenlerde en fazla calışılmış ve teyit edilmis bir bulgudur. Bu çalışmada biz şizofrenlerde BBT bulgularıyla serebral kan akımı ve magnetik rezonans görüntûleme ile ilgili çalışmaların gözden geçirdik.
Computed Tomography, Magnetic Resonance Imaging, Cerebral Blood Flow and Schizophrenia
The development of new technologies for studying brain structure during life such as the computed tomography (CT) scan made it possible to examine large samples of carefully diagnosed patients and matched controls Johnstone published the first of now nearly 100 reports of CT scans in schizophrenia. In this study of elderly schizophrenic and control males the size of the lateral ventricules as a function of total brain area was significantly larger in the schizophrenic patients.
Over the past 15 [year]s, lateral ventricul enlargement has become the most exhaustively studied single phenomenon in the field of schizophrenia research and possibly the most replicable biological finding in psychiatry. In this article, we reviewed CT, cerebral blood flow studies and Magnetic Resonance Imaging techniques in schizophrenia.

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