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Yıl:2019; Cilt: 20; Sayı: 4>> Özet
TAM METİN
Bağımlılık Dergisi; 2019;20(4):206-213
Alkol Kullanım Bozukluğu Olan Hastalarda Tam Kan Sayımı Parametreleri ve Lenfositle İlişkili Oranlar
S Baykara, Ş Kaya, ŞŞ Berk
Fırat Üniversitesi, Elazığ
Amaç: Ağır alkol tüketimi olan alkol kullanım bozukluğu (AKB) hastalarında tam kan sayımı (CBC) parametreleri ve lenfosit-ilişkili oranların araştırılması planlandı. Yöntem: En az 10 yıldır alkol kullanımı olan 75 kişiden ‘bağımlı grup’ oluşturuldu. CBC parametreleri, alkol detoksifikasyonuna başlanmadan önce istenen tetkiklerin değerlendirilmesiyle elde edildi. 75 sağlıklı kişiden ‘kontrol grubu’ oluşturuldu. Bulgular: Alkol kullanım miktarı 6.04±1.45 birim/gün, alkol kullanım süresi ortalama 27.62±8.68 yıl idi. Beyaz küre (WBC), nötrofil sayısı, yüzdesi, monosit sayısı, yüzdesi, nötrofil-lenfosit oranı (NLO), monositlenfosit oranı (MLO) bağımlı grubunda daha yüksek olmak üzere, gruplar arasında anlamlı farklılık vardı. Lenfosit yüzdesi, eozinofil sayısı, yüzdesi, bazofil yüzdesi, RBC, eozinofil-lenfosit oranı (ELO) kontrol grubunda daha yüksek olmak üzere gruplar arasında anlamlı farklılık vardı. Sonuç: CBC, kısa sürede yapılan ucuz bir tetkik olarak, ağır alkol tüketen AKB tanılı hastalarda teşhis koymada ve takipte enflamatuvar süreçler ve immünolojik sistem hakkında bilgi veren yöntem olarak kullanılabilir
Complete Blood Count Parameters and Lymphocyte-Related Ratios in Patients with Alcohol Use Disorder
Objective: The study aimed to determine complete blood count (CBC) parameters, lymphocyte-related ratios in alcohol use disorder (AUD) patients with heavy alcohol use. Method: The dependent group included 75 individuals with history of alcohol use for at least 10 years. CBC parameters were obtained by evaluating the required tests before alcohol detoxification was initiated. The control group included 75 healthy individuals. Results: Alcohol use was 6.04 ± 1.45 units/day and the mean duration of alcohol use was 27.62 ± 8.68 years. There were significant differences between the groups based on white blood cell (WBC), neutrophil count, percentage, monocyte count, percentage, neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), favoring the dependent group. There were significant differences between the groups based on lymphocyte percentage, eosinophil count, percentage, basophil percentage, RBC and eosinophil to lymphocyte ratio (ELR), favoring the control group. Conclusion: CBC can be used as a rapid and inexpensive examination in AUD patients with heavy alcohol consumption to obtain information about inflammatory processes. and immunological systems which may be useful in AUD diagnosis treatment and follow-up.

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