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Yıl:1995; Cilt: 32; Sayı: 1>> Özet
Nöropsikiyatri Arşivi; 1995;32(1):27-31
Multipl Sklerozda Görülen Psikiyatrik Bozukluklar
Ş Gök, S Özkan
İ.Ü. İstanbul Tıp Fakültesi, Psikiyatri ABD
Multiple Skleroz en sık görülen demyelizan hastalıktır. En sıklıkla 20-40 yaşlan arasında görülür. Etiyolojisi bilinmemektedir, otoimmün hastalıklardandır. Multifokal nörolojik bulgulara ek olarak çeşitli psikiyatrik bozukluklar ortaya çıkmaktadır. Kognitif fonksiyonlarda değişiklikler ve afektif bozukluklar son yıllarda artan sıklıkta incelenmeye başlanmıştır. Çalışmamızda, multiple skleroz hastalarında görülen psikiyatrik bozukluklar incelenmiştir. Kesin MS tanısı alan 30 hastada, sistematik psikiyatrik tanı DSM-III-R'a göre konulmuştur. Beck depresyon skalası, STAI Anksiyete skalası, Hastalık Üzüntü Ölçeği, Fiziksel performans skalası (Karnofsky), GHQ-60 ve klinik psikiyatrik değerlendirme yapılmıştır. Psikometrik fonksiyonlar ölçülmüştür. Çalışmamızda depresyon prevalansı % 33.3, anxiete % 20.0, hipomani % 13.3 ve organik beyin sendromu % 3.3 bulunmuştur. Fiziksel ve duygusal travmatik deneyimlerin MS'in prespitasyonunda ve tedavi cevabının şiddetinde önemli rol oynadığı tesbit edilmiştir.
Multiple Sclerosis and Psychiatric Abnormalities
Multiple Sclerosis is the most commmon demyelinating disease. The onset is in young between 20 and 40 [year]s of age. The aetiology is unknown. In addition to multifocal neurologic signs, which have a tendency to relaps and remit, a variety of symptoms suggesting psychiatric illness have been reported. In multiple sclerosis, behavioral changes including alterations in cognitivite functions and affective abnormalities, have been recognized with increasing frequency in recent [year]s. A systematic psychiatric and neurologic evaluation was performed on 30 patients with definite MS. The psychiatric diagnosis is based upon DSM III-R Beck Depression scale, STAI Anxiety scale, Illness distress scale, Physical performance scale (Karnofsky), General Health Questionnary, a clinical psychiatric evaluation were performed. The psychometric functions were measured. The prevalance of depression in our study is % 33.3 anxiety % 20.0, hypomania % 13.3 and organic brain syndrome % 3.3 Physically and emotionally traumatic experiences play an important role in the presipitation of MS and m the severity response to treatment of MS.

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