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Yıl:2018; Cilt: 29; Sayı: 1>> Özet
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Türk Psikiyatri Dergisi; 2018;29(1):22-30
Şizofreni Hastalarında İçgörünün Psikopatoloji ve Nöropsikolojik İşlevlerle İlişkisi  
A Tiryaki, A Karahan, FC Arslan
Karadeniz Teknik Üniversitesi, Trabzon
Amaç: Bu çalışmanın amacı, şizofreni hastalarında içgörünün farklı boyutlarının klinik değişkenler, belirti şiddeti ve bilişsel işlevlerle ilişkisini araştırmaktır. Yöntem: Bu kesitsel tanımlayıcı çalışmada Karadeniz Teknik Üniversitesi (KTÜ) Tıp Fakültesi Psikiyatri polikliniğine ayaktan başvuran ve DSM-IV’e göre şizofreni tanısı konan 66 hasta değerlendirmeye alınmış- tır. Tüm hastalar DSM için yapılandırılmış klinik görüşme (SCID-I), Pozitif ve Negatif Belirtileri Değerlendirme Ölçeği (PNBDÖ), Calgary Şizofrenide Depresyon Ölçeği (CŞDÖ), İçgörünün Üç Bileşenini De- ğerlendirme Ölçeği (İÜBDÖ) ile değerlendirilmiştir. Hastaların bilişsel işlevlerini değerlendirmek amacı ile Wisconsin Kart Eşleme Testi, Sözel Akıcılık Testi, İz Sürme Testi A ve B ve Rey İşitsel ve Sözel Öğrenme Testi ve Bellek testi uygulanmıştır. Bulgular: Hastaların İÜBDÖ ile değerlendirilen içgörü düzeyleri PNBDÖ pozitif, negatif, genel psikopatoloji belirti şiddeti, Sözel Akıcı- lık Testi ve İz Sürme Testi A ve B puanları ile ilişkili saptanmıştır. Çoklu değişkenli doğrusal regresyon analizinde PNBDÖ pozitif, Sözel Akıcılık Testi ve İz Sürme Testi A puanları İÜBDÖ toplam puanının yordayıcı- ları olarak tespit edilmiştir. Sonuç: Şizofrenide içgörü ile klinik belirtiler arasındaki ilişki hastalığın klinik seyrine ve psikopatoloji belirti şiddetine bağlı olarak değişebilmektedir. Bu çalışma bulguları içgörü ile bilişsel işlevler arasındaki iliş- kide frontal yürütücü işlevlerin önemini vurguluyor olabilir.
The Relationship of Insight with Psychopathology and Neuropsychological Functioning in Patients with Schizophrenia
Objective: The aim of this study was to investigate the relationship of the different dimensions of insight with clinical variables, symptom severity, and cognitive functions in patients with schizophrenia. Method: In this cross-sectional descriptive study, 66 out patients that applied to the Karadeniz Technical University, Psychiatry Clinic and were diagnosed with schizophrenia according to DSM-IV were evaluated. The patients were evaluated with Structured Clinical Interview for DSM (SCID-I), the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia (CDSS), and the Schedule for Assessing the Three Components of Insight (SAI). Wisconsin Card Sorting Test, Verbal Fluency Test, Trail Making Test A and B and Rey Auditory Verbal Learning Test were applied to assess the cognitive function of each patient. Results: The insight levels of the patients that were evaluated with SAI were found to be correlated with PANSS positive, negative, and general psychopathology symptom severity as well as Verbal Fluency Test and Trail Making Test A and B scores. In the multiple linear regression analysis, PANSS positive, Verbal Fluency Test and Trail Making Test A scores were determined the contributors of SAI total score. Conclusions: The relationship between insight and clinical symptoms may change depending on the course of the disease and severity of symptoms. These findings emphasize the importance of frontal executive function in the relationship between insight and cognitive functions.

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