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Yıl:2000; Cilt: 10; Sayı: 4>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 2000;10(4):213-227
Şizofrenide ilaç sağaltımı
L Gülseren, A Erol
Atatürk Eğitim ve Araştırma Hastanesi Psikiyatri Kliniği, İzmir
Şizofrenide ilaç sağaltımı klorpromazinin bulunması ile başlamıştır. Giderek daha başka antipsikotik ilaçların da sentezlenmeye başlanması psikotik hastaların akıl hastanelerinden çıkarak topluma karışması ile sonuçlanmıştır. Klasik antipsikotik ilaçların ardından ekstrapiramidal sendroma yol açmayan ve negatif belirtiler üzerine de etkili olan atipik antipsikotik ilaçların bulunması sağaltımda yeni ufuklar açmıştır. Bu yazıda şizofreni sağaltımında kullanılan ilaçlar gözden geçirilmiş ve temel sağaltım ilkeleri tartışılmıştır.
Pharmacotherapy in schizophrenia
Pharmacotheraphy in schizophrenia begins with the discovery of chlorpromazine. Later the synthesis of other various antipsychotics has led psychotic patients to get out of hospitals and live in the society. After classical antipsychotics, the discovery of atypical antipsychotics which do not cause extrapyramidal syndrome and that are effective on negative symptoms as well has brought new perspectives to the treatment of schizophrenia. This paper reviews pharmeceutical agents that are used for the treatment of schizophrenia and discusses basic treatment principles.

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