Dergi Ara >>
Yıl:2017; Cilt: 4; Sayı: 3>> Özet
TAM METİN
Türk Uyku Tıbbı Dergisi; 2017;4(3):95-103
İnme Uyku İlişkisi: Bir Derleme
M Batum, AK Ak, H Yılmaz
Celal Bayar Üniversitesi, Manisa
İskemik inme; gelişmekte olan ülkelerde mortalitenin üçüncü, özürlülüğün ise birinci nedeni olarak karşımıza çıkmaktadır. Uyku bozuklukları ile serebrovasküler risk faktörleri arasındaki ilişki iyi tanımlanmakta ve patofizyolojisinde farklı mekanizmalar yer almaktadır. İskemik inme; hipoksi, artmış uyanıklık reaksiyonları, uyku kalitesindeki azalma, serbest oksijen radikallerinin artışı, enflamatuvar mekanizmaların aktivasyonu, endotelyal fonksiyon bozukluğu, ateroskleroz, hipertansiyon ve insülin direnci gibi birçok yolu etkilemektedir. Uyku bozuklukları, birden farklı doğrudan veya dolaylı mekanizma ile inme patolojisine katkıda bulunmaktadır. Uyku bozukluklarının değiştirilebilir serebrovasküler risk faktörleri arasında olması nedeniyle uyku bozukluklarının tanısı, yönetimi ve önlenmesi konusunda farkındalığın artması çok önemlidir.
The Relationship of Stroke and Sleep: A Review
Ischemic stroke appears the third leading cause of mortality and the first cause of disability in developing countries. The relationship between sleep disorders and cerebrovascular risk factors is well defined and there are different mechanisms in pathophysiology. Ischemic stroke affects many pathways, such as hypoxia, increased wakefulness reactions, decreased sleep quality, increased free oxygen radicals, inflammatory mechanisms activation, endothelial dysfunction, atherosclerosis, hypertension, and insulin resistance. Sleep disturbances contribute to stroke pathology through multiple direct or indirect mechanisms. Due to the fact that sleep disorders are among the changeable cerebrovascular risk factors, it is very important to raise awareness about the diagnosis, management and prevention of sleep disorders.

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