Dergi Ara >>
Yıl:1992; Cilt: 3; Sayı: 3>> Özet
Türk Psikiyatri Dergisi; 1992;3(3):227-230
Geç Diskineziler ve Beyin İşlev Bozukluğu
E ÖZMEN, O ARKONAÇ
Geç diskinezi duyarlı bireylerde uzun süreli nöroleptik tedavi esnasında gelişen istemsiz hareketlerle karakterize bir sendromdur. Asıl olarak ağız-dil-yüz bölgelerini tutan koreoatetoid ve/veya distonik hareketler şeklindedir. Ancak diğer bölgelerdeki istemli kasları da etkileyebilmektedir. Uzun süredir tanınıyor olmasına karşın risk faktörleri, etiyolojisi ve tedavisi hakkında çok az şey bilinmektedir. Bu makalede, son literatür bilgilerinin ışığında geç diskinezilerde beyin işlev bozukluğunun varlığına ilişkin kanıtlar gözden geçirilmiştir.

Tardive Dyskinesia and Brain Dysfunction
Tardive dyskinesia (TD) is a syndrome of involuntary movements that develops in predisposed individuals during long-term neuroleptic treatment. TD manifests as choreoathetoid and/or dystonic movements primarily in the orollingual-facial region, but can also affect other voluntary muscles. Despite being identified over two decades ago, little is known about the risk factors and etiology of this disabling syndrome with even less information known about its treatment. In this article, through a review of the recent literature, evidence supporting the brain dysfunction in tardive dyskinesia is presented.

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