Dergi Ara >>
Yıl:2016; Cilt: 3; Sayı: 2>> Özet
TAM METİN
Türk Uyku Tıbbı Dergisi; 2016;3(2):26-33
Obstrüktif Uyku Apnesi ve Kanser
CEK Demir
Acıbadem Üniversitesi, İstanbul
Obstrüktif uyku apnesi (OUA) sık görülen ve ciddi morbidite ve mortalite ile seyreden bir hastalıktır. OUA hastalarında kanser insidansının arttığı, hastalığın hızlı progrese olduğu ve kansere bağlı ölümlerin artmakta olduğuna dair her geçen gün daha fazla bilgiye sahip olmaktayız. İntermittan hipoksi, oksidatif stres ve uyku fragmantasyonu kanser gelişiminden sorumlu tutulmaktadır.
Obstructive Sleep Apnea and Cancer
Obstructive sleep apnea (OSA) is a common disorder which is associated with increased morbidity and mortality. There is growing evidence that patients with OSA have higher incidence of cancer, accelerated progression and cancer mortality. Intermittent hypoxia, oxidative stress and sleep fragmentation are hold responsible for cancer development.

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