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Yıl:2016; Cilt: 27; Sayı: 3>> Özet
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Türk Psikiyatri Dergisi; 2016;27(3):161-169
Antidepresan İlaç Tedavisi Başlanan Hastalarda Anksiyete ve Depresyon Belirtileri ile Cinsel İşlevlerdeki Değişikliklerin Değerlendirilmesi: 3 Aylık Doğal İzlem Çalışması
MG Ülgen, G Güleç
Eskişehir Osmangazi Üniversitesi, Eskişehir
Amaç: Bu çalışmada, psikiyatri polikliniğine ayaktan başvuran ve antidepresan tedavi başlanan hastalarda, 3 aylık dönem boyunca ruhsal belirtilerindeki gerilemeye paralel cinsel işlevlerdeki değişim ve bu değişimin anksiyete, depresyon belirtileri ile ilişkisinin araştırılması amaçlanmıştır. Yöntem: Psikiyatri polikliniğine ardı sıra başvuran, antidepresan tedavi başlanan 82 hasta çalışmaya alınmıştır. Hastalara ilk görüşmede, 1., 2. ve 3. aylarda Hamilton Depresyon Derecelendirme Ölçeği, Hamilton Anksiyete Değerlendirme Ölçeği, İşlevselliğin Genel Değerlendirilmesi Ölçeği ve Arizona Cinsel Yaşantılar Ölçeği uygulanmıştır. Bulgular: Tedavi öncesinde hastaların 57’sinde (%69,50) cinsel işlev bozukluğu saptanmıştır. Bu gruptaki 24 hastada (%42,11) çalışma sonunda ACYÖ puanlarına göre artık cinsel işlev bozukluğu saptanmazken, 33 hastanın (%57,89) puanlarının ise halen bozukluk düzeyinde olduğu saptanmıştır. Tedavi öncesinde cinsel işlev bozukluğu olmayan gruptaki 25 hastanın 8’inde (%32) izlem sonunda cinsel işlev bozukluğu saptanmıştır. Cinsel işlev bozukluğu, anksiyete ve depresif belirtilerden bağımsız olarak hastaların işlevselliğini etkilemektedir. Sonuç: Çalışmamızın sonuçları psikiyatrik hasta popülasyonunda cinsel işlev bozukluğu oranının oldukça yüksek olduğuna işaret etmektedir. Klinisyenlerin tedavi başlangıcında ve takibinde ruhsal belirtilerinin yanında cinsel işlevlerini de göz önüne alarak tedavinin fayda-zarar dengesini belirlemesi uygun olacaktır.
Evaluation of Changes in Anxiety and Depression Symptoms, and Sexual Functions in Patients Receiving Antidepressants: 3 Months-Long Naturalistic Follow-Up Study
Objective: The aim of this study was to study the change in sexual functions within 3 months period following the initiation of antidepressant treatment in psychiatry outpatients, and its relationship with the change in anxiety and depression symptoms. Material and Method: Eighty two patients, who consecutively applied to the psychiatry outpatient clinic and who were prescribed antidepressants, were included in the study. Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, General Assessment of Functioning Scale and Arizona Sexual Experience Questionnaire (ASEC) were administered to the patients at the first interview, then repeated on a monthly basis during 3 months. Results: Fifty seven of the patients (69.50 %) has been diagnosed with sexual dysfunctions prior to the antidepressant treatment. During the third month after the antidepressant treatment, 24 patients in this group (42.11%) showed no impairment in ASEC scores, whereas 33 patients’ (57.89%) scores were still at impairment level. Eight patients out of 25 (32%) who weren’t diagnosed with sexual dysfunctions prior to the treatment were later diagnosed with sexual dysfunctions. Sexual dysfunctions correlated with patients’ level of functioning, separately from anxiety and depression symptoms. Results: Our study results show that the sexual dysfunction rate is quite high in psychiatric patients population. However, sexual dysfunctions rate which can be related to antidepressant treatment is 36%. It would be appropriate for clinicians to determine benefit-loss balance by considering patients’ mental syndromes together with sexual functions.

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