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Yıl:2016; Cilt: ; Sayı: 9>> Özet
TAM METİN
Literatür Sempozyum; 2016;(9):5-10
Vitiligo ve Aleksitimi
ŞT Acar, E Ayyıldız, A Camkurt, Tİ Kaya, AD Başterzi, V Yıldırım
Mersin Üniversitesi, Mersin
Amaç: Dermatolojik hastalıklarda ruhsal hastalıklar daha sık görüldüğü öne sürülmektedir. Vitiligo gibi immün sistemle ilişkili dermatolojik hastalıklarda hastalığın ortaya çıkışı ve seyri ile ruhsal hastalıklar ve psikolojik stresörler ilişkili olabilir. Ayrıca aleksitiminin otoimmün özellikli hastalıklarda sık görüldüğü bilinmektedir. Bu çalışmanın amacı, vitiligo hastaları ve kontrol grubu arasındaki aleksitimi, depresyon ve anksiyete düzeyleri farklılıklarının karşılaştırılmasıdır. Yöntem: Vitiligolu (25’ i kadın, 27’ si erkek) 52 hasta ile (26’ sı kadın, 26’ sı erkek) yaş ve cinsiyet uyumlu 52 sağlıklı birey kontrol grubu olarak çalışma kapsamına alındı. Hastalar ve kontrol grubu, sosyodemografik veri formu, Hamilton Depresyon Ölçeği(HAM-DÖ), Hamilton Anksiyete Ölçeği(HAMAÖ), Toronto Aleksitimi ölçeği-26(TAÖ) ile değerlendirildi. Bulgular: Vitiligo hastalarında HAM-DÖ ve HAM-AÖ ortalama puanları anlamlı şekilde yüksekti (p<0.001 ve p<0.001). TAÖ puanları vitiligo hastalarında anlamlı derecede yüksek olarak gözlendi(p=0.005). Bu sonuçlara göre, vitiligo grubunun daha aleksitimik olduğu saptanmıştır. Vitiligo hastalarından 20 kişinin(%38), kontrol grubundan 8 kişinin(%18) aleksitimik olduğu saptanmıştır. Sonuç: Çalışmamızda daha önceki çalışmalara benzer şekilde anksiyete ve depresyon daha yüksek oranda saptanmıştır. Ancak bugüne kadar vitiligo hastalarında aleksitimi ile ilgili yapılmış çok kısıtlı sayıda araştırma yayınlanmıştır. Çalışmamızda vitiligo hastalarında aleksitimi düzeylerinin daha yüksek olduğu tespit edilmiştir. Aleksitiminin immün fonksiyonlarda bozulmaya neden olduğu ve aleksitimik bireylerin psikolojik, endokrin ve immün sonuçları olan fark etmedikleri bir kronik strese maruz kaldıkları ileri sürülmektedir. Çalışmamız aleksitimi ile vitiligo arasında etiyolojik bir ilişki olabileceğini desteklemektedir.
Vitiligo and Alexithymia
Objective: The aim of this study is to compare differences of alexithymia, depressive and anxiety symptoms between vitiligo patients and control group. Method: A total of 52 patients (27 male, 25 female) with vitiligo and 52 age-and gender-matched healthy controls (26 male, 26 female) were enrolled in the study. Both patients and controls were evaluated using a form for sociodemographic data, Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), Toronto alexithymia scale-26(TAS-26). This study performed in Mersin Üniversity Medicine Faculty. Results: The mean scores of HAMD and HAMA were significantly higher in patients with vitiligo. (p<0.001 ve p<0.001). TAS-26 scores in patients with vitiligo were higher than in controls(p=0.005) According to these resultsi vitiligo group were found to be more alexithymic. 20 people(%38) from vitiligo patients and 8 people from control group were found to be alexithymic. Conclusion: The present study found that alexithymia were more common in vitiligo patients. It has been suggested that alexithymics may suffer from unnoticed chronic stress with physiological, endocrine, and immune consequences, and that alexithymia is associated with impaired immune response. We suggest that alexithymia may play a role in the pathogenesis of vitiligo. More detailed studies with larger patient numbers are required on this topic.

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