Dergi Ara >>
Yıl:2015; Cilt: 53; Sayı: 2>> Özet
TAM METİN
Yeni Symposium; 2015;53(2):50-52
Aripiprazole bağlı ağır parkinsonizm: Olgu sunumu
İ İnanlı, Am Çalışkan, A Kürkcü, İ Eren
Konya Eğitim ve Araştırma Hastanesi, Konya
Aripiprazol, D2 ve 5-HT1A reseptör parsiyel agonisti ve 5-HT2A reseptör antagonisti olup, atipik bir antipsikotiktir. Yapılan çalışmalarda plaseboya yakın oranda ekstrapiramidal belirtilere neden olduğu bildirilmiştir. Ama aripiprazole bağlı ekstrapiramidal belirtilerin görüldü- ğü çalışma ve olgu bildirimleri bulunmaktadır. Sundu- ğumuz olguda aripiprazol 10 mg/gün kullanırken ağır parkinsonizm gelişmiş ve ilaç kesildikten sonra kaybolmuştur.
Aripiprazole induced severe parkinsonism: a case report
Aripiprazole, a D2 and 5-HT1A receptor partial agonist and 5-HT2A receptor antagonist, is an atypical antipsychotic. Previous studies indicated that the rate of extrapyramidal symptoms caused by aripiprazole is very close to that of placebo. However, there are studies and case reports in the literature describing aripiprazole-induced extrapyramidal symptoms. In this case, while using 10 mg/day of aripiprazole, severe parkinsonism appeared and they disappeared after discontinuation of the drug.

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