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Yıl:2014; Cilt: 25; Sayı: 1>> Özet
Türk Psikiyatri Dergisi; 2014;25(1):60-64
Metalik Civa Zehirlenmesi ve Nöropsikolojik Etkileri: Bir Olgu Sunumu
E Çöp, SEÇ Kültür, EE Bakar
Sami Ulus Kadın Doğum Çocuk Sağlığı ve Hastalıkları EAH, Ankara
Cıva, merkezi sinir sistemini etkileyen çok toksik bir ağır metaldir. Bu yazıda okuldan eve getirilen cıvaya dört gün maruz kalması sonrası cıva zehirlenmesi tanısı alan 15 yaşında bir kız hasta aktarılacaktır. Hasta, pediyatri bölümü tarafından izlenmekte iken duygusal değişkenlik, unutkanlık, disinhibisyon, dürtüsellik yakınmaları ile çocuk ve ergen ruh sağlığı ve hastalıkları bölümüne danışılmıştır. Hastaya olanzapin 2,5 mg/gün başlanmıştır. İlk değerlendirmede uygulanan nöropsikolojik test paketi ile hastanın nöropsikolojik işlevselliği değerlendirilmiş ve bozucu etki altında kurulumu sürdürebilme ve dikkat (Stroop Testi TBAG Formu), sözel akıcılık ve kategori değiştirebilme (Sözel Akıcılık Testi/SAT), sözel kısa süreli ve uzun süreli bellek ve tanıma (İşitsel Sözel Öğrenme Testi/İSÖT) becerilerinde bozukluk saptanmıştır. Dokuz aylık izlem sonunda hastanın belirtilerinin klinik olarak düzeldiği ve zekâ puanlarında artış olduğu, dikkatini toplama becerisi ve sürdürebilme kapasitesinin arttığı gözlenmiştir. İlk değerlendirmede düşük olduğu gözlenen Stroop Testi TBAG Formu, SAT ve İSÖT’deki başarısı artmış ve yaşıtlarıyla uyumlu hale gelmiştir. Hasta klinik olarak merkezi sinir sistemi tutulumu ve okullarda cıva ile temas ile ilgili koruyucu önlemler alınmasına duyulan ihtiyaç yönünden tartışılacaktır.
Metallic Mercury Poisoning and Neuropsychological Effects: A Case Report
Mercury is an extremely toxic heavy metal that can devastate central nervous system. We present the case of a 15 year old adolescent with mercury intoxication following 4 days of exposure to elemental mercury at home who was consulted by department of pediatrics with complaints of demonstrated emotional lability, memory impairment, disinhibition, and impulsivity. Olanzapin 2,5 mg/day was initiated. Her neuropsychological performance was evaluated by a neuropsychological test battery at initial examination. Deterioration in neuropsychological functions like interference effect and attention (Stroop Test TBAG form), verbal fluency and switching to other category (Verbal Fluency Test, /(VFT), verbal short term and long term memory and recognition (Auditory Verbal Learning Test, /(AVLT) was detected. In 9 months follow up period her complaints resolved. Initial neuropsychological deficits were also fully recovered at follow up. There was an increase in intelligence scores with increased ability to pay and sustain attention. She had better performance at Stroop Test TBAG form, VFT and AVLT which was similar to her normal peers’. In this case report, the clinical aspects of central nervous system involvement in mercury intoxication and protection from potential toxic effects of laboratory materials like mercury at schools were discussed. School administrators should be aware of and parents and students should be given necessary protective information.

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