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Yıl:2012; Cilt: 2; Sayı: 3>> Özet
TAM METİN
Journal of Mood Disorders; 2012;2(3):133-138
TSSB ve iki uçlu bozukluk ek tanısı olan cinsel istismara uğramış ergenlerde farmakolojik tedavinin idaresi: Bir olgu serisi
G Celik, A Tahiroğlu, A Avcı
Çukurova Üniv. Tıp Fak., Adana
Cinsel istismara uğramış ergenlerde, travma sonrası stres bozukluğunun belirtileri bipolar bozukluk ve davranım bozukluğu gibi diğer bozuklukların belirtileriyle sıklıkla örtüşmektedir. Bu yazıda, beş olgunun klinik izlemi sırasında bipolar bozukluk ve travma sonrası stres bozukluğu ayırıcı tanısında yaşanan güçlükler tartışılacaktır. Bu beş olgunun ayırıcı tanısı ve seyri yatarak tedavi ve taburculuk dönemleri boyunca değerlendirildi. Bu olguların tamamı aile üyesi veya yabancı bir erişkin tarafından fiziksel, duygusal ya da cinsel olarak istismar edilmiş idi. Olguların ikisinin ailesinde bipolar bozukluk öyküsü vardı. Bir olguda travma sonrası stres bozukluğu belirtileri için verilen antidepresan tedaviye bağlı manik atak oldu. Disosiyatif belirtiler ve irritabilitenin yaygın olduğu bu karışık klinik durumun tedavisinde ikinci kuşak antipsikotikler ve duygudurum düzenleyicileri kullanıldı. Travma sonrası stres bozukluğu ve bipolar bozukluk belirtilerinin çoğu oldukça benzerdir. Bununla birlikte, bipolar bozukluğu olan çocuk ve ergenler cinsel istismar için artmış risk taşırlar veya bunun tersi de doğrudur. Klinisyenler bu olguların klinik ve farmakolojik yönetimi sırasında iki durumu da göz önüne almalıdırlar.
Pharmacological management of sexually abused adolescents with comorbid ptsd and bipolar disorder: a case series
Posttraumatic stress disorder (PTSD) symptoms in sexually abused adolescents often overlap with many other diseases, such as conduct disorder and bipolar disorder (BD). In this paper, the difficulties encountered in making the differential diagnosis of BD and PTSD will be discussed with clinical outcomes of five cases. The follow-up findings and differential diagnosis of five cases were evaluated throughout their hospitalization and after discharge. All of these cases have been abused physically, sexually or emotionally by their family members or adult strangers. Two cases had a positive family history of BD. One case switched to manic state due to antidepressant treatment prescribed for PTSD symptoms. Dissociative symptoms and irritability were common and atypical antipsychotics and mood stabilizers have been used for the treatment of these mixed clinical states. Many symptoms of PTSD and BD are very similar. Moreover, children and adolescents with BD are under greater risk for sexual abuse or vice versa are also correct. Clinicians should take into consideration both clinical states during clinical and pharmacological management of these patients.

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