Dergi Ara >>
Yıl:2012; Cilt: 5; Sayı: 1>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2012;5(1):20-28
Dikkat Eksikliği/Hiperaktivite Bozukluğunun Nörobiyolojisi
D Ünal, B Uluğ
Hacettepe Üniv. Tıp Fak., Ankara
Dikkat Eksikliği/Hiperaktivite Bozukluğu (DEHB), oldukça sık görülen bir gelişimsel bozukluk olmasına rağmen, DEHB'nin etyolojisi ve patofizyolojisi ile ilgili bilinenler sınırlıdır. Bugüne kadar yapılan çalışmalar, DEHB'nin genetik yatkınlık zemininde, çeşitli çevresel etkenlerin de katkısıyla oluşan bir nörogelişimsel aksama sonucu oluştuğunu ve DEHB'li kişilerin nörobiyolojik yapılarının farklı olduğunu ortaya koymuştur. Bu gözden geçirme yazısında DEHB'nin nörobiyolojik temelleri, DEHB ile ilişkili genetik, nöropsikolojik, nörofarmakolojik, çevresel etkenlerin araştırıldığı çalışmalar ve nörogörüntüleme çalışmaları gözden geçirilerek aktarılmıştır.
Neurobiology of Attention Deficit/Hyperactivity Disorder
Although Attention Deficit/Hyperactivity Disorder (ADHD) is a prevelant developmental disorder, what we know about the etiology and pathophysiology of ADHD is limited. To date, performed researches have indicated that ADHD is the result of a neurodevelopmental delay caused by genetic and environmental effects . Also the neurobiological structure of people who are suffering from ADHD has been found different from normal. In this review, the neurobiological bases of ADHD is explicated by summarizing the results of genetic, neurophyscological, neuropharmacological, environmental factor researches about ADHD.

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