Dergi Ara >>
Yıl:2012; Cilt: 5; Sayı: 1>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2012;5(1):14-19
Dikkat Eksikliği/Hiperaktivite Bozukluğunun Etiyolojisinde Çevresel ve Genetik Etmenler
C Şengül, H Herken
Pamukkale Üniversitesi Tıp Fakültesi, Denizli
Dikkat eksikliği/hiperakitivite bozukluğu (DEHB) dikkatsizlik, dürtüsellik ve hiperaktivite ile karakterize gelişimsel bir bozukluktur. DEHB'nun yüksek kalıtılabirliği, evlat edinme, aile, ikiz ve klasik moleküler genetik araştırmalarda gösterilmiş. Son zamanlarda ise tüm genomu inceleyen ilişkilendirme ve kopya sayısı değişiklikleri çalışmalarının sayısı artmaktadır. Epigenetik ise DEHB genetiğinin farklı yönlerini aydınlatmaya ve gen çevre ilişkisini anlamamıza yardım etmektedir Bu yazıda biz DEHB genetiği üzerine mevcut literatürü gözden geçirmeyi amaçladık
Environmental and Genetic Factors in Etiology of Attention Deficit/Hyperactivity Disorder
Attention deficit/hyperactivity disorder (ADHD) is a developmental disorder which is characterized by inattention, impulsiveness and hyperactivity. High heritability of ADHD was shown with twin, adoption, family and classic molecular genetic studies. Recently, genome wide association and copy number variation studies are on the rise. Epigenetics, identified different aspects of genetic of ADHD and helps us to understand gene environment interaction. In this paper, we aimed to review current literature on ADHD genetics

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