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Yıl:2012; Cilt: 22; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2012;22(1):83-85
Ergen hastada sertralin kullanımıyla ilişkili oromandibular distoni
S Sarısoy, H Özyürek, G Sarısoy
Bafra Nafiz Kurt Devlet Hastanesi, Samsun-Türkiye
Selektif serotonin gerialım inhibitörleri (SSGI) bir çok psikiyatrik
hastalığın tedavisinde yaygın olarak kullanılmaktadır.
Sertralin bir miktar dopamin gerialım inhibisyonu da yapan
bir selektif serotonin gerialım inhibitörüdür. Uyuklama,
sinirlilik, terleme, uyuşukluk, uykusuzluk, baş dönmesi,
bulantı, titreme, deri döküntüsü, hazımsızlık, iştah kaybı,
baş ağrısı, ishal, ejakülasyon bozukluğu, ağız kuruluğu ve
kilo kaybı en sık görülen yan etkileridir. Sertralin extrapiramidal
yan etkilere ise oldukça nadir olarak sebep olur. Biz
bu yazımızda sertralin kullanımı sonucu ortaya çıkan bir
oromandibular distoni vakasını sunduk. Bilgilerimize göre
literatürde ergenlik yaş grubunda sertralin kullanımı sonucu
oluşan distoniye dair vaka sunumu yoktur.
Oromandibular dystonia associated with sertraline in an adolescent patient
Selective serotonin reuptake inhibitors (SSRIs) are widely
prescribed to treat a variety of psychiatric disorders.
Sertraline is a relatively selective serotonin reuptake
inhibitor with some dopamine reuptake inhibitor activity.
The most common side effects of sertraline are sleepiness,
nervousness, increased sweating, somnolence, insomnia,
dizziness, nausea, tremor, skin rash, dyspepsia, loss of
appetite, headache, diarrhea, abnormal ejaculation,
dry mouth, and weight loss. Extrapyramidal side effects
associated with sertraline have been very rarely reported.
We here report a case of oromandibular dystonia secondary
to sertraline use in an adolescent patient. To the best of our
knowledge, this is the first report of dystonia associated
with sertraline in an adolescent patient.

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