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Yıl:2011; Cilt: 21; Sayı: 4>> Özet
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Klinik Psikofarmakoloji Bülteni; 2011;21(4):364-367
Atomoksetin kullanımına bağlı motor tikler: Olgu sunumu
M Küçükköse, NB Özbaran, SG Köse
GATA Çocuk ve Ergen Psikiyatrisi, Ankara
Dikkat eksikliği ve hiperaktivite bozukluğu (DEHB) hastalarında, tik bozukluğu (TB) ya da Tourette sendromu (TS) eş hastalanım oranları yüksektir. DEHB ve TB/TS komorbiditesi yanısıra, DEHB tedavisinde kullanılan psikostimulan ilaçların var olan tiklerde artışa ya da yeni tik oluşumuna neden olabileceği de bilinmektedir. Bu nedenle, DEHB ile birlikte TB/TS olan hastalarda seçici noradrenalin geri alım inhibitörü olan atomoksetin, hem DEHB belirtilerinde etkili olması hem de TB/TS tedavisinde kullanılabilecek bir alternatif olması nedeniyle önemli bir tedavi seçeneği olarak klinik pratiğe girmiştir. Ancak son yayınlarda, atomoksetin'i n mevcut tiklerin artışına ya da yeni tik oluşumuna neden olmadığına ve hatta tikleri azalttığına dair genel bilgilerimizin aksini bildiren sunumlar da görülmektedir. Bu olgu sunumunda, atomoksetin kullanımına bağlı var olan tiklerin şiddetinde artış ve yeni tik oluşumu görülen bir olgu sunumu literatür ışığında tartışılmıştır.

Anahtar Kelimeler :
Motor tics due to atomoxetine use: a case report
The comorbidity ratio of attention deficit and hyperactivity disorder (ADHD) and tic disorders (TD) or Tourette's syndrome (TS) is very high. It is also known that, psychostimulant use in the treatment of ADHD can increase existing tics or cause new tics. Therefore, a selective noradrenaline reuptake inhibitor, atomoxetine, which is effective in the treatment of tics and ADHD symptoms, was introduced into clinical practice as a treatment choice in patients with ADHD and TD/TS comorbidity. However, recently there have been reports about reverse effects of atomoxetine on tics. In this report, we discuss a clinical case that had an increase in existing tic severity and developed new tics during atomoxetine treatment .

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