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Yıl:2011; Cilt: 14; Sayı: 3>> Özet
TAM METİN
Klinik Psikiyatri Dergisi; 2011;14(3):164-172
Majör Depresyon ve Anksiyete Bozukluğunun Birlikte Görüldüğü Durumların Klinik Özellikleri: Karşılaştırmalı Bir Çalışma
H Karadag, S Örsel, A Kart, B Özcaltepe, H Türkçapar, E Kayran
Ankara Dışkapı Eğitim ve Araştırma Hastanesi
Amaç: Anksiyete ve duygulanım bozuklukları arasındaki farklılıklar daha net tanımlanmakla birlikte iki bozukluğun ortak bir psikopatolojinin farklı klinik görünümleri olduğuna yönelik tartışmalar da artmıştır. Bu çalışmada depresyon ile anksiyete bozukluğunun hem tanı hem de belirti düzeyinde ortak ve farklı özelliklerinin araştırılması amaçlanmıştır. Yöntem: Çalışmaya DSM-IV'e göre yapılandırılmış klinik görüşme (SCID-I) ile depresyon ve/veya anksiyete bozukluğu tanısı alan 113 ardışık hasta alındı. Hastalar anksiyete bozukluğu, depresyon, karışık anksiyete ve depresif bozukluk (KAD) epizodları olan üç gruba ayrıldı. Özgeçmiş ve sosyodemografik özellikleri içeren bilgi formu, Hamilton Depresyon (HAM-D) ve Anksiyete (HAM-A) ve işlevselleğin genel değerlendirmesi (İGD) uygulandı. Bulgular: Depresyon grubunda 15 (%13.3), anksiyete grubunda 48 (%42.5), karışık anksiyete depresyon grubunda 50 hasta (%44.2) vardı. Başlangıç yaşı depresyon grubunda daha ileri yaştaydı. Anksiyete grubunda kırsal, KAD grubunda kentsel doğumlu oranları yüksekti. KAD grubundaki hastaların %80'inde birincil anksiyete bozukluğu, %20'sinde birincil depresyon epizodu saptandı. HAM-A psişik puanları anksiyete, korkular madde puanları depresyon grubunda daha düşüktü. HAM-D depresif sendromun şiddeti ve depresif belirti puanları açısından üç grup arasında anlamlı fark vardı. Sonuç: Bu çalışmanın sonuçları, korkuların anksiyete epizodları olanlarda daha sıklıkla olduğunu, depresyon belirtilerinin gruplar arası farklılıkta öne çıktığı, anksiyeteden depresyon epizodlarına doğru kronolojik bir gelişim olduğunu desteklemektedir.
Clinical Features of Patients with both Major Depression and Anxiety Disorders Episodes: A Comparative Study
Objectives: The differences among anxiety and mood
disorders have become more sharply defined but a larger debate has arisen about whether these two conditions
share a common psychopathology or not. We aimed to
investigate sociodemographic, common and different
features of depression and anxiety on both syndrome
and symptom levels. Method: 113 consecutive patients
diagnosed by Structured Clinical Interview for DSM-IV
(SCID-I) were recruited. Patients were divided into three
diagnostic groups: depression (n=15), anxiety (n=48)
and depression-anxiety disorder episodes (MAD) (n=50).
Symptomatology was assessed by Hamilton Depression
(HRSD) and Anxiety (HARS) Rating scale, global assessment of functionality scale (GAF) for functionality levels.
Results: There were 15 (%13.3) in depression, 48
(%42.5) in anxiety, 50 (%44.2) patients in MAD groups.
Onset age of the symptoms of the present diagnosis was
latest at depression group. The rural birth rates in anxiety, urban birth rate in MAD groups were more frequent.
In MAD group %80 of the patients had primer anxiety
disorder episode and %20 had primer depression
episode. HAM-A psychologic item scores in anxiety
group, fears item scores were lower in depression group.
There were significant difference between three groups
in terms of HAM-D depressive syndrom severity and
depressive items. Conclusion: The results of our study
suggest that fears were more frequent in anxiety group,
but depressive symptoms were predominant in the differences of the groups and anxiety may progress chronologically towards the depression.

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