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Yıl:2011; Cilt: 1; Sayı: 2>> Özet
TAM METİN
Journal of Mood Disorders; 2011;1(2):49-54
Türkiye’de iki uçlu bozuklukta Lityum kullanılmasının 40 yıllık öyküsü
M Nebioğlu, N Konuk
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, İstanbul
İki Uçlu Mizaç Bozukluğu’nun klasik tedavi seçeneği olarak lityum’un kullanılış tarihçesi Türkiye’de de dünyadaki kullanımına paralel seyretmiştir. Bu duruma, FDA (US Food & Drug Administration) tarafından lityumun sürdürüm tedavisinde onaylanması sürecinde etkili olan çalışmaları yapan Dr. Mogens Schou’nun Türkiye’de konferanslar vermek yolu ile gösterdiği etkin çabanın katkısı olduğunu düşünmekteyiz. Bu editoryal yazıda Lityum’un klinik uygulamada rutin kullanımı ile ilgili öncül klinik uygulamaları başlattığını ifade eden Dr. Niyazi Uygur’la yapılan biyografik çalışmadan alıntılar da bulunmaktadır. Bu çalışma vesilesi ile Türkiye’de yapılmış lityum kullanımı ile ilgili kaynakça da ulaşılabilen en eski tarihlere kadar taranmış ve okuyucuya sunulmuştur. Ulaştığımız literatür bilgileri, ülkemizde de 1970’li yıllarda lityum kullanmaya başlamış ve halen tedavisini sürdüren iki uçlu mizaç bozukluğu hastalarının bile mevcudiyetine işaret etmektedir. Türk psikiyatrisi pek çok alanında olduğu gibi, iki uçlu mizaç bozukluğu tedavisinde de lityum devrimine çok erkenden katılarak öncü rolünü sergilemiştir.
40 [year]s history of Lithium treatment in bipolar disorder in Turkey
The historical background of using lithium as a choice of classical treatment of bipolar disorder in Turkey had a trend parallel to that of the world. We think that what contributed to this end was the successful efforts of Dr. Mogens Schou in giving lectures on the issue in Turkey. Dr. Schou was the one who conducted the trials which contributed to the process of approving lithium as a maintenance medication by the FDA (US Food & Drug Administration). This editorial article contains quotations from the biographic study made with Dr. Niyazi Uygur who stated that he had started the initial trials relating to the routine use of lithium in clinical practices. Owing to this study, the bibliography on the use of lithium in Turkey was screened back to the earliest dates and presented to the reader. The information in the literature we could reach indicates that lithium started to be used in 1970s also in Turkey and there still are bipolar patients whose treatment is in progress at present. As in many areas, Turkish Psychiatry has joined the lithium (in treatment of bipolar disorder) revolution at a very early stage and demonstrated its leading role.

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