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Yıl:2010; Cilt: 47; Sayı: 4>> Özet
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Nöropsikiyatri Arşivi; 2010;47(4):348-350
Brusella Vasküliti: Olgu Sunumu
M Gencer, R Türkoğlu, B Yıldırım, Y Çetinkaya, H Tireli
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, İstanbul
Bruselloz gelişmekte olan ülkelerde halen sık rastlanan bir hastalıktır. Bruselloz'da santral sinir sistemi tutulumu yaklaşık %3-13 arasında görülmektedir. Akut, subakut veya kronik menenjit, meningoensefalit, poliradikülonevrit, myelit ve vaskülit en sık görülen nörobruselloz tablolarıdır. Bu yazıda derin serebral penetran damarların vaskülitik tutulumu neticesinde inme (sol hemiparezi) gelişen ve bazal meningeal tutuluma bağlı sol 6. kraniyal sinir tutulumu olan 20 yaşında erkek bir nörobruselloz olgusunun sunulması amaçlanmıştır. Olgumuzda beyin omurilik sıvısında (BOS) lenfositer pleositoz ve protein artışı ile birlikte kan ve BOS'ta brusellaya karşı antikor pozitifliği saptanmıştır. Brusella'nın endemik olarak görüldüğü ülkemizde, inme ve benzeri klinik tabloların ayırıcı tanısında nörobruselloz da akla gelmelidir.
Brucella Vasculitis: Case Report
Brucellosis is still common in developing countries. Central nervous system involvement in brucellosis has been reported to be 3-13%. Acute, subacute or chronic meningitis, meningoencephalitis, polyradiculoneuritis, myelitis and vasculitis are the most common features of neurobrucellosis. The aim of this report is to present a case of neurobrucellosis. A 20- [year]-old male had a stroke (left-sided hemiparesis) due to vasculitic involvement of penetrating cerebral vessels and left abducens palsy related to basal meningeal involvement. Examination of cerebrospinal fluid (CSF) revealed lymphocytic pleocytosis and increased protein as well as raised antibody titers for brucella were detected in the blood and CSF. Neurobrucellosis should be considered in the differential diagnosis of stroke and related disorders because of its endemic nature in our country.

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