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Yıl:2010; Cilt: 47; Sayı: Özel>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2010;47(Özel):35-39
Tremor Tedavisinde Botulinum Toksini
AB Tokçaer
Gazi Üniversitesi Tıp Fakültesi, Ankara
Tremor klinik pratikteki en yaygın istemsiz hareket bozukluklarından biridir. Tremorun nedenleri heterojen olduğundan tremor yönetimi için tek, ortak bir yaklaşım bulunmamaktadır. Tremorun ilaç tedavisi bazen etkili olsa da distonik tremor, primer yazma tremoru, ses tremoru, esansiyel baş tremoru gibi tremorun bazı alt tipleri oral ilaçlara yanıtsızdır. Distoniye eşik eden tremor şiddetinin botulinum toksini A (BoNT) injeksiyonundan sonra belirgin olarak azaldığına ilişkin gözlemler BoNT'nin tremorda alternatif bir tedavi olabileceğini önermektedir. Bu gözden geçirme yazısının amacı farklı tremor tiplerinde BoNT tedavisi hakkındaki literatürü özetlemektir.
Treatment of Tremor with Botulinum Toxin
Tremor is one of the most frequently encountered involuntary movement disorders in clinical practice. The causes of tremor are heterogeneous, therefore, a unique approach to the management of tremor is not available. Drug management of tremor is sometimes effective, however, there are subtypes of tremor such as dystonic tremor, primary writing tremor, voice tremor and essential head tremor, which are unresponsive to oral medication. The observation of marked amelioration of severity of tremor accompanying dystonia after botulinum toxin type A (BoNT) injection suggests that BoNT can be an alternative treatment option for tremor. In this review, our aim was to summarize the published literature on BoNT treatment for different subtypes of tremor.

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