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Yıl:2010; Cilt: 47; Sayı: Özel>> Özet
TAM METİN
Nöropsikiyatri Arşivi; 2010;47(Özel):30-34
Larengeal Botulinum Toksini Uygulamaları
KS Orhan, B Başaran, M Ulusan, G Hafız
İstanbul Üniversitesi İstanbul Tıp Fakültesi
Larenksin temel işlevi alt hava yolu proteksiyonunu sağlamaktır; ayrıca respirasyon ve fonasyona da yardımcı olur. Çeşitli sebeplere bağlı olarak bu kaslarda hipertonisite ve/veya spazm gelişimi, solunum, yutma ve ses problemlerine yol açabilir. Larenksin adduktor spazmodik disfonilerinin tedavisinde botulinum toksini uzun yıllardır başarı ile kullanılmaktadır. Krikofarengeal disfajiler, larengeal tikler, larengeal granülom ve paradoksal vokal kord hareketi gibi hastalıklar diğer kullanım alanlarını oluşturur. Botulinum tokisininin geri dönüşümlü etkisi destrüktif cerrahi girişimlere karşı avantaj sağlamış, tıbbi pratikte güvenli ve yaygın kullanımını mümkün kılmıştır. Bu yazıda kısaca larenks anatomi ve fizyolojisi hakkında bilgi verilmiş, larengeal botulinum toksini uygulamaları gözden geçirilmiştir.
Botulinum Toxin Applications in the Larynx
The primary function of the larynx is protection of the lower respiratory system and, in addition, it facilitates respiration and phonation. Hypertonicity and/or spasm of the laryngeal muscles due to several reasons can cause abnormalities in respiration, digestion and voice. Botulinum toxin has been used successfully in the treatment of adductor spasmodic dysphonia (laryngeal dystonia) for several [year]s. Cricopharyngeal dysphagia, laryngeal tics, laryngeal granulomas and paradoxical vocal cord motions are the other areas, where botulinum toxin can be used. Because of its reversible effects, botulinum toxin is superior to the destructive surgical techniques. In this article, the anatomy and physiology of the larynx is described briefly and botulinum toxin applications in the larynx are discussed.

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