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Yıl:2010; Cilt: 47; Sayı: 3>> Özet
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Nöropsikiyatri Arşivi; 2010;47(3):260-262
Ergen Hastada Aripiprazole Bağlı Nöroleptik Malign Sendrom: Bir Olgu Sunumu
Ö Kamışlı, Ö Özcan, Y Kaplan, C Özcan
İnönü Üniversitesi Tıp Fakültesi, Malatya
Nöroleptik Malign Sendrom(NMS) sıklıkla antipsikotik kullanımına bağlı, nadir görülen bir sendromdur. Bu sendromda genellikle hipertermi, kas rigiditesi, otonomik bozukluklar, mental durum değişiklikleri, tremor, serum kreatinfosfokinaz yüksekliği ve lökositoz görülür. Aripiprazol şizofreni tedavisinde kullanılan yeni bir antipsikotiktir. Bu yazıda otizm ve mental retardasyon tanısı ile takip edilen ergen bir hastada düşük doz aripiprazol kullanımı ile ortaya çıkan NMS tablosu tartışılacaktır.
Aripiprazole and Neuroleptic Malignant Syndrome in an Adolescent Patient: A Case Report
Neuroleptic malignant syndrome (NMS) is a rare disorder seen most often in patients exposed to antipsychotic medications. This syndrome is generally manifested by hyperthermia, muscle rigidity, autonomic instability, altered mental status, tremors, elevated serum creatinine phosphokinase and leucocytosis. Aripiprazole is a new antipsychotic approved for the treatment of schizophrenia, In this report we discussed a case of a mentally retarded and autistic adolescent whom developed NMS after low dose aripiprazole.

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