Dergi Ara >>
Yıl:2009; Cilt: 12; Sayı: 4>> Özet
TAM METİN
Klinik Psikiyatri Dergisi; 2009;12(4):197-200
Fluvoksamin Kullanımı Sırasında Ortaya Çıkan Distoni: Bir Olgu
BB Annagür, L Tamam
Konya Numune Hastanesi
Selektif serotonin geri alım inhibitörleri depresyon başta olmak üzere, anksiyete bozuklukları, obsesif kompulsif bozukluk, yeme bozuklukları, dürtü kontrol bozuklukları gibi çeşitli ruhsal bozuklukların tedavisinde genellikle ilk tercih edilen ilaçlardır. SSRI kullanımına bağlı EPS bulguları olarak; akatizi, distoni, parkinsonizm ve tardif diskinezi bildirilmiştir. Akut distoni psikiyatrik bir acildir. Genellikle antipsikotik kullanımı sonucunda gelişir. Ancak antiemetik ve antidepresanlar ile de gelişebilir. Bu olguda obsesif kompulsif bozukluk tanısı ile fluvoksamin kullanan bir hastada tedavinin ikinci ayında doz artırımı sırasında gelişen bir distoni tablosu sunulmuştur. Literatürde fluoksetin ile bildirilen olgu örnekleri vardır. Bu olgu fluvoksamin kullanımı sırasında görülmesi ve Türkçe yayımlarda daha önce bildirilmemesi bakımından önemli bulunarak hazırlanmıştır. Klinisyenler SSRI'ların ekstrapiramidal sistem yan etkileri olabileceğini akıllarında tutmalı ve doz artırımlarında dikkatli olmalıdırlar.
Dystonia During Fluvoxamine Treatment: A Case Report
Selective serotonin reuptake inhibitors are generally firstchoice
drugs, particularly in the treatment of depression,
anxiety disorder, eating disorder and various psychiatric
disturbances, such as impulse control disorder. Acathisia,
dystonia, parkinsonism and tardive dyskinesia have been
reported as the extrapyramidal system findings associated
with use of selective serotonin reuptake inhibitors.
Acute dystonia is a psychiatric emergency. It develops
due to use of antipsychotics. However, it has also been
reported to occur due to use of antiemetics and antidepressants.
In this paper, we present a case with dystonia
which developed during fluvoxamine treatment in the
second [month] during administration of increased dose
on the patient with obsessive compulsive disorder. There
is case reports related to the use of fluoksetin in the literature.
This case was considered to be noteworthy to
publish, in that it occurred during use of fluvoxamine
and it has not been reported in the Turkish literature so
far. Clinicians should always keep in their mind that there
may be extrapyramidal side effects of selective serotonin
reuptake inhibitors and should be careful when increasing
doses.

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