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Yıl:2010; Cilt: 3; Sayı: 2>> Özet
Türkiye Klinikleri Psikiyatri Özel Dergisi; 2010;3(2):67-74
Şizofreni ve Metabolik Sendrom
MA Ateş, O Durmaz
GATA Haydarpaşa Eğt. Hastanesi
Şizofreni hastalarında metabolik sendrom (MetS) a oldukça sık rastlanmaktadır. Belkide bu nedenle şizofreni hastalarında kardiyovasküler risk ve ölüm prevalansı normal populasyona göre oldukça yüksektir. Metabolik sendrom için risk faktörleri arasında kötü diyet, sedanter hayat gibi sağlıksız yaşam tarzları, antipsikotik kullanımı ve özellikle son kanıtlardan sonra genetik faktörleri de içerecek şekilde şizofreninin kendisinin de bulunduğu anlaşılmaktadır. Şizofreni hastalarının tedavisinde multidisipliner bir yaklaşım gerekmektedir. Psikiyatristler bu hastalarda gerekli metabolik taramaların yapılmasından ve mevcut fiziksel hastalıkların tedavisinin ihmal edilmemesinden de sorumludurlar. Rutin takip, metabolik riski olmayan antipsikotik ilaç seçimi ve sağlıklı yaşam tarzı eğitimi MetS riskini azaltmakta kritik rol oynamaktadır.
Schizophrenia And Metabolic Syndrome
Metabolic syndrome is highly prevalent in patients with schizophrenia. Probably, for this reason cardiovascular risk and premature mortality are highly prevalent in patients with schizophrenia compared to normal population. Metabolic risk factors are attributable to unhealthy lifestyle, including poor diet and sedentary life, antipsychotic agents and schizophrenia itself underlying genetic factors. In the treatment of patients with schizophrenia, multidisciplinary assessment of psychiatric and medical conditions is needed. Psychiatrist should be responsible for the implementation of the necessary screening assessments and referral for treatment of any physical illness. It is needed to be aware of the potential metabolic side effects of antipsychotic medication and to include them in the risk/benefit assessment when choosing a specific antipsychotic. Routine monitoring, preferential use of metabolically neutral antipsychotics and lifestyle education are critical to minimizing of metabolic risk.

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