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Yıl:2010; Cilt: 20; Sayı: 1>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 2010;20(1):98-100
Yüksek dozda trospiyum klorür kullanımıyla ortaya çıkan manik atak: Bir olgu sunumu
R Bilici, GK Uğurlu, S Sağam, T Güven, M Uğurlu
Elazığ Ruh Sağlığı ve Hastalıkları Hastanesi
Mani tipik olarak iki uçlu bozukluğun parçası olarak görülmekle birlikte nörolojik nedenler, metabolik durumlar, infeksiyonlar, polisitemi ve bazı ilaçlarla ilişkili olarak da görülebilir. Bu durum ikincil mani olarak tanımlanır. Antidepresanlar, steroidler, asiklovir, izoniazid, amfetaminler, sulbutiamin, propofenon, prosiklidin, dekstrometorfan gibi ilaçlarla ilişkilendirilen birçok ikincil mani olgusu bildirilmiştir. Bu olguda aşırı aktif mesane tedavisinde kullanılan seçici olmayan antikolinerjik etkili trospiyum klorürün yüksek dozda kullanımı sonrasında ortaya çıkan manik atak sunulmuştur
High dose trospium chloride induced manic episode: a case report
Mania typically occurs as part of bipolar affective disorder, but it may occur secondary to neurological causes, metabolic conditions, infections, polycythemia and some of drugs. This kind of a situation is named as secondary mania. Various secondary mania cases have been reported related with antidepressants, steroids, acyclovir, isoniazid, amphetamines, sulbuthiamine, propafenone, procyclydine and dextrometorphan. In this casereport, we report a manic episode that developed with high dose use of trospium chloride, a non-selective, anticholinergic drug which is used in the treatment of overactive bladder.

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