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Yıl:2010; Cilt: 20; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2010;20(1):94-97
Behçet hastalığı ve geç başlayan hızlı döngülü iki uçlu duygudurum bozukluğu: Bir olgu sunumu
AG Hariri, G Yalçı, C Ünsal, H Meteris, M Bilici
Erenköy Ruh ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi, İstanbul-Türkiye
Behçet hastalığı (BH) tanısı ile 16 yıldır izlenen 48 yaşındaki kadın hasta 41 yaşında iken iki uçlu duygudurum bozukluğu (İUDB) tanısı almıştı. Hasta son karma atağı nedeniyle hastanemizde yatarak tedavi görürken, her iki hastalığının birbirlerine karşılıklı etkisi incelendi. Bilindiği gibi, Behçet hastalığı ile duygudurum bozukluklarının karşılıklı etkileşimi ve hastanın yaşam kalitesini değiştirmesi söz konusu olabilmektedir. Bu hastada, BH'dan yaklaşık 9 yıl sonra başlayan İUDB'nun son 2 yıldır hızlı döngülü hale dönüştüğü, buna karşılık BH'nın duygudurum bozukluğu başlamasından sonra gittikçe düzelerek nerdeyse tam olarak iyileşme gösterdiği belirlenmiştir. Duygudurum ataklarının hızlı hale dönüşmesinin hastanın yaşamını güçleştirdiği ve tedaviye uyumunu bozduğu gözlemlendi. Yapılan literatür incelemesinde BH ve İUDB birlikteliği ile ilgili az sayıda yayın bulunduğu görülmüştür. Bu yazıda, nadir görülen bu birlikteliğin literatürdeki benzerleriyle karşılaştırılması ve olası nedenleri tartışılmıştır
Behçet?s disease and late onset rapidly cycling bipolar affective disorder: a case report
A 48- [year] old woman who is suffering from Behcet's disease (BD) for 16 [year]s was diagnosed as having bipolar affective disorder (BAD) at the age of 41. Correlative effects of her both illness have been examined when she has been treated in our hospital because of her new mixed episode. It has known that these kind of illnesses have different correlative effects about each other and therefore they might insuence the patient's quality of life adversely. In our patient, bipolar disorder which developed about 9-10 [year]s after the first physical manifestations of BD has come in to rapidly cycling in last 2 [year]s, the exact opposite of this situation, the BD ameliorated after beginning of bipolar disorder , practically it was in the remission. Rapidly cycling feature of her BP illness deteriorated patient's life and comprimised her treatment. There are only a few publication in the current literature about comorbidity of Behçet's Disease and BAD. In this case report, relationship and potential causes of this unusual situation is discussed compared to similar situations in the literature

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