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Yıl:2010; Cilt: 20; Sayı: 1>> Özet
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Klinik Psikofarmakoloji Bülteni; 2010;20(1):45-49
Israrcı gelişimsel kekemeliği olan genç yetişkinlerde otonom sinir sistemi işlevinin tilt testi ile değerlendirilmesi
B Özdemir, A Doruk, C Çelik, B Amasyalı, M Çiyiltepe, C Özcan
GATA, Ankara
Amaç: Otonom sinir sistemi konuşmanın motor düzenlenmesinde önemli rol oynar. Gelişimsel kekemelikte sempatik ve parasempatik sistemler arasında bir dengesizliğin söz konusu olabileceği varsayılmaktadır. Bu çalışmanın amacı ısrarcı gelişimsel kekemeliği olan genç yetişkinlerde tilt testi (TT) sonuçlarının değerlendirilmesidir.

Yöntem: Çalışmaya ısrarcı gelişimsel kekemeliği olan 27 hasta ile yaş olarak eşleştirilmiş 22 normal konuşan sağlıklı kontrol alındı. Kekeme denekler bir dil-konuşma terapisi uzmanı tarafından Kekemelik Şiddet Ölçeği ile derecelendirildi. Sonrasında denekler otonom sinir sistemi tilt testi ile değerlendirildi.

Bulgular: Kekeme grubunda kekemeliğin ortama başlangıç yaşı 7.44±3.75 yıldı (aralık: 3-17). Kekeme grubunda 18 denek (% 66.7) pozitif TT yanıtı gösterirken, normal konuşan grupta 2 denek (% 9.1) TT pozitişiği gösterdi (p< 0.01). Uygulamanın başlangıcında istirahatte ortalama nabız, sistolik ve diastolik kan basınçları iki grup arasında anlamlı farklılık göstermemesine karşın, TT uygulaması bitiminde, kekemelerin ortalama sistolik ve diastolik kan basınç değerleri normal konuşan gruba oranla daha düşüktü (sırasıyla p=0.001 and p=0.003).

Tartışma: Çalışma sonuçları kekemelerde TT pozitif yanıtının daha sık olduğunu göstermektedir. Bu çalışmanın bulguları, önceki çalışmamızdaki otonom sinir sistemi düzensizliğine işaret eden sonuçları desteklemektedir.
Evaluation of autonomic nervous system function with tilt table testing in young adults with persistent developmental stuttering
Objective: Autonomic nervous system plays a key role on motor speech and its regulation. An imbalance has been suggested to exist between the sympathetic and parasympathetic nervous systems in developmental stuttering. The aim of the present study was to evaluate the results of tilt table (TT) testing in young adults with persistent developmental stuttering.

Method: Twenty-seven patients with persistent development stuttering and 22 age-matched healthy controls were examined. Patients were examined by the speech- [language] specialist using the Stuttering Severity Instrument. Afterwards, their autonomic nervous system function was examined by using the TT test.

Results: In the stutterers, the mean onset of stuttering was 7.44±3.75 [year]s (range of 3 to17 [year]s). Eighteen stutterers (66.7%) showed a positive TT response, whereas 2 normal speakers (9.1%) had a positive TT response (p< 0.01). Although mean pulses, systolic and diastolic blood pressures at the rest did not differ significantly between the two groups, stutterers had lower systolic and diastolic blood pressure values than those of normal controls (p=0.001 and p=0.003 respectively) at the end of TT testing.

Discussion: We conclude that a positive TT response is observed more often in the stutterers. The findings of the present study support the results of our previous report indicating that the stutterers have an autonomic nervous system dysregulation

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