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Yıl:2009; Cilt: 1; Sayı: 1>> Özet
Geriatri ve Geriatrik Nöropsikiyatri Dergisi; 2009;1(1):43-51
Demansta Depresyon
İ Kırpınar
Atatürk Üniversitesi Tıp Fakültesi Psikiyatri AD, Erzurum
Demans ve depresyon, yaşlı nüfusta en sık görülen mental bozukluklardır.Ayrıca, demans tanısı alan hastalar eşlik eden depresyon da sergileyebilirler. Demanslı hastaların % 50'si ndenfazlasını etkileyen depresyon, hasta ve bakım vericileri için ciddi olumsuz sonuçlara yol açabilir. Demans ve depresyon birlikteliğini araştıran çalışmalar oldukça farklı görülme oranları bildirmektedir. Bildirilen görülme sıklıkları arasındaki farklar, birbirinden farklı tanısal yöntemler ve ölçütler başta olmak üzere çeşitli faktörlere bağlıdır. Demanslı hastalardaki depresyonların tanısı, doğal gidişi, etyolojisi ve tedavisi üzerine yapılmış çalışmalar azdır ve çelişkilidir. Demansta depresyon tanısının konması zorluklar içerir. Demanslı hastanın muayenesindeki zorluklar yanında, demansta görülen depresyonların tipik olmayan görünümleri de bunun başlıca nedenlerinden biridir. Bu yazıda; demansta görülen depresyonların uygun biçimde tanı ve tedavisine yardımcı olmak amacıyla literatürdeki çalışmalar gözden geçirilmektedir. Ayrıca; depresyon ve demans potansiyel mekanizmalar incelenerek açıklanmaktadır.
Depression in Dementia
Dementia and depression are the most frequent mental disorders diagnosed in the elderly population. Additionally, patients with an established diagnosis of dementia can present with coexisting depression. Affecting up to 50% of patients with dementia, depression is associated with serious negative consequences for patients and their caregivers. There is wide variation in the reported incidence rates of coexistence of depression and dementia. The difference in reported incidence rates has been attributed to a number of factors, including the employment of non-uniform diagnostic methods and criteria. Yet available studies on the diagnosis, natural course, etiology, and treatment of depression in patients with dementia have been few and equivocal. In this article, studies from the literature are reviewed that aid in accurate diagnosis, and treatment of depression in dementia. Furthermore, the relationship between depression and dementia is explored by examining potential mechanisms.

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