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Yıl:2009; Cilt: 47; Sayı: 3>> Özet
TAM METİN
Yeni Symposium; 2009;47(3):120-122
Panik Bozukluk ve Chiari I Malformasyonu Birlikteliği: Bir Vak'a Sunumu
M Kuloğlu, A Çayköylü, O Ekinci, Y Albayrak, O Deniz
Atatürk Eğitim ve Araştırma Hastanesi Psikiyatri Kliniği Ankara, Turkey
Chiari I malformasyonu sıklıkla baş ağrısı veya serebellum, beyin sapı ve medulla spinalisin servikal bölümünün disfonksiyonuna ilişkin semptomlar ile tanınan ve serebellar tonsillerin foramen magnumdan aşağıya doğru yer değiştirmesi ile karakterize bir konjenital beyin anomalisidir. Bildiğimiz kadarıyla bu anomali ile bir anksiyete bozukluğu arasındaki ilişkiyi târif eden sınırlı literatür bilgisi mevcuttur. Biz, ilk safhada panik semptomları ile başvuran daha sonra Chiari I malformasyonu olduğu tespit edilen bir hasta rapor ediyoruz. Vak'aya malformasyonu için cerrahi tedavi uygulanamamıştır. Psikotrop tedavi sonrası anksiyete semptomlarında izafî klinik düzelme görülmüştür. Bu vak'a fizik ve nörolojik muayene ile laboratuar bulgularının normal olmasından dolayı gözden kaçmış bir lezyonu araştırmanın önemine vurgu yapmaktadır. Ayrıca panik bozukluğu ile Chiari I malformasyonu arasında sık olmayan bir komorbiditeyi göstermektedir.
Comorbid Panic Disorder and Chiari I Malformation: A Case Report
Chiari I malformation is a congenital hindbrain anomaly characterized by downward displacement of the cerebellar tonsils through the foramen magnum, commonly presents in patients with headache or symptoms of dysfunction of the cerebellum, brainstem, and cervical spinal cord. To our knowledge, there is a limited literature about any anxiety disorder in association with this anomaly. We describe a patient who firstly presented with panic symptoms and who later proved to have Chiari I malformation. The patient had no surgical intervention for this malformation and had a relative clinical improvement of her anxiety symptoms after psychotropic medication. This case highlights the importance of searching for a lesion that might otherwise go undetected in light of normal physical and neurological examinations and laboratory findings. Also, it demonstrates a rare comorbidity of Chiari I malformation and panic disorder.

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