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Yıl:2009; Cilt: 19; Sayı: 2>> Özet
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Klinik Psikofarmakoloji Bülteni; 2009;19(2):159-163
Pitüiter adenomu olan depresif bir hastada fluoksetine bağlı galaktore: Olgu sunumu
ABO Girayalp
Ankara Dr. Abdurrahman Yurtaslan Onkoloji Eğitim ve Araştırma Hastanesi
Fluoksetin, depresyon ve anksiyete bozuklukları başta olmak üzere pek çok psikiyatrik bozukluğun tedavisinde yaygın olarak kullanılmakta olan selektif serotonin geri alım inhibitörlerinden (SSGİ) birisidir. Galaktore, SSGİ nin de içinde bulunduğu ilaçların yanısıra pekçok tıbbi duruma bağlı olarak ortaya çıkabilen bir klinik tablodur. Bu yazıda; otuz yedi yaşında, depresyon nedeniyle fluoksetin tedavisi almakta iken galaktore gelişen bir olgu sunulmuştur. Olguda serum prolaktin seviyesinde yükseklik, bilgisayarlı tomografi ve manyetik rezonans görüntüleme tetkiklerinde de pitüiter mikroadenoma ile uyumlu kitle lezyonunun varlığı tespit edilmiştir. Bu bağlamda, tıbbın tüm alanlarında olduğu gibi psikiyatride de ortaya çıkan klinik tabloların değerlendirilmesinde komorbit (eş zamanlı) tanıların tespiti , tedavi ve prognoz açısından son derece önemlidir.
Galactorrhea due to şuoxetine in a patient with depression and a pituitary adenoma: A case report
Fluoxetine is one of the selective serotonin reuptake inhibitors (SSRI) used widely for the treatment of various psychiatric disorders, especially depression and anxiety. Galactorrhea is a clinical manifestation which may ocur due to medications including SSRIs and also may be due to various medical conditions. In this context; a thirty-seven [year] old who received suoxetine treatment for depression and developed galactorrhea is presented. An increase in serum prolactin level with a mass consistent with pituitary adenoma was determined by computer tomography and magnetic resonance imaging. As in all fields of medicine, comorbid diagnosis is extremely important in psychiatry in order to analyze the clinical conditions for treatment and prognosis.

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