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Yıl:2004; Cilt: 11; Sayı: 1>> Özet
TAM METİN
Çocuk ve Gençlik Ruh Sağlığı Dergisi; 2004;11(1):44-49
Dikkat Eksikliği Hiperaktivite Bozukluğu Olan Erkek Çocuklarda İşitsel Olayla İlgili Potansiyeller
Ö Yorbık, MF Özdağ, P Kırmızıgül, ÜH Ulaş, K Hamamcıoğlu, O Vural
GATA, Tıp Fakültesi, Çocuk Psikiyatrisi AD., Ankara.\r\n\r\n
Amaç: Bu çalışmanın amacı dikkat eksikliği hiperaktivite bozukluğu (DEHB) olan çocuk ve ergenlerin parietal ve frontal alanlardaki P1, N2 ve P3 dalgalarının amplitüd ve latenslerini sağlıklı kontrol grubuyla karşılaştırmaktır. Yöntem: Kırküç DEHB olan ve 23 sağlıklı çocuğun paryatal ve frontal bölgelerdeki olayla ilgili potansiyel latensleri [paryetal P3 (PP3L), P1 (PP1L), N2 (PPN2L); frontal P1 (FP1L), N2 (FN2L), P3 (FP3L)] ve amplitüdleri [paryatal P3 (PP3A), P1 (PP1A), N2 (PN2A); frontal P1 (FP1A), N2 (FN2A), P3 (FP3A)] işitsel oddball paradigm görevi sırasında kaydedilmiştir. Bulgular: DEHB olan çocuklarda, normallere göre, PP3L ve FP3L önemli derecede uzun, PP3A, FN2A ve FP3A ise küçüktü (tüm p değerleri <.05). PP1L, PP1A, PN2L, PN2A, FP1L, FP1A ve FN2L parametreleri bakı- mından iki grup arasında farklılık saptanmadı. Tartışma: DEHB grubundaki daha küçük P3 amplitüdü ve uzun P3 latensi işleyen belleğin yenilenmesindeki sorunlara işaret edebilir. DEHB olan çocuklarda daha küçük N2 amplitüdü frontal inhibisyondaki yetersizlikleri gösterebilir. Bu bulgular DEHB'nin frontal disfonksiyon ile birlikte olduğunu düşündürmektedir.
Auditory Event Related Potentials in Boys with Attention Deficit Hyperactivity Disorder
Objective: The aim of the present study were to compare event related brain potentials (ERPs) indices between children with attention deficit hyperactivity disorder (ADHD), and normals. Method: ERPs indices, latencies of parietal P3 (PP3L), P1 (PP1L), N2 (PPN2L), and frontal P1 (FP1L), N2 (FN2L), P3 (FP3L), and amplitudes of parietal P3 (PP3A), P1 (PP1A), N2 (PN2A), and frontal P1 (FP1A), N2 (FN2A), and P3 (FP3A), using an auditory oddball paradigm were recorded in 43 boys with ADHD, and in 23 normal children. Results: PP3L and FP3L were significantly longer and PP3A, FN2A, and FP3A smaller in children with ADHD compared to normals (all p values <.05). No significant differences were found in other ERPs indices. Conclusion: Smaller P3 amplitude and longer P3 latency in ADHD group may be indicate ineffective working memory updating. Smaller N2 amplitude in ADHD group may reflect an atypical frontal inhibition process. These results suggested that ADHD is associated with frontal dysfunction.

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