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Yıl:2008; Cilt: 18; Sayı: 3>> Özet
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Klinik Psikofarmakoloji Bülteni; 2008;18(3):208-221
Obsesif kompulsif bozukluk ve obsesif kompulsif spektrum bozukluklarında tedavi: Fluvoksamin’in yeri
N Dilbaz, O Karamustafalıoğlu
Ankara Numune Eğitim ve Araştırma Hastanesi, 2. Psikiyatri Kliniği, Ankara-Türkiye
Obsesif kompulsif bozukluk sık görülen ve kişide yeti kaybına yol açan bir hastalıktır. OKB belirtileri kişinin işlevselliğini engelleyecek düzeye geldiğinde tedavi edilmelidir. Serotonin geri alım inhibitörleri başta olmak üzere ilaç tedavisi ve bilişsel davranışcı tedavi OKB tedavisinde güvenilir ve etkili birinci basamak tedavisi olarak önerilmektedir. Fluvoksamin obsesif kompulsif bozukluk tedavisinde serotonin geri alım inhibitörleri arasında en çok veri tabanı olandır. Serotonin gerialım inhibitörleri obsesif kompulsif bozukluk birinci aşama tedavisinde yer alırlar. Çoğu obsesif kompulsif spektrum bozuklukları tedavisinde de etkinlikleri bilinmektedir. Fluvoksamin’in hem obsesif kompulsif bozukluk ve hem de obsesif spektrum bozukluklarında etkinliği birçok çalışmada gösterilmiştir. Bu yazıda OKB hastasına yaklaşım, doğru tanı koyma ve tedavi ilkeleri ile fluvoksamin’in OKB ve Obsesif spektrum bozuklukları tedavisinde ki rolü gözden geçirilmiştir.
Treatment of obsessive compulsive-disorder and obsessive compulsive spectrum disorder: fluvoxamine
Obsessive-compulsive disorder is common debilitating psychiatric disorder. OCD should be treated when symptoms interfere with functioning. Pharmacotherapy mainly serotonin reuptake inhibitors and cognitive behavioral psychotherapy are recommended as safe and effective first-line treatments in OCD: Fluvoxamine is the serotonin reuptake inhibitor with the largest database in the treatment of obsessive compulsive disorder. Serotonin reuptake inhibitors are the first line treatment in obsessive compulsive disorder.Their efficacy is well known in most of the obsessive compulsive spectrum disorders.Fluvoxamine’s efficacy has shown in the treatment of both obsessive compulsive disorder and obsessive compulsive spectrum disorders in many studies. In this article psychiatric management, assessment and treatment of OCD and the role of suvoxamine on the treatment of OCD and Obsessive Compulsive spectrum disorders was reviewed.

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