Dergi Ara >>
Yıl:2007; Cilt: 15; Sayı: 3>> Özet
TAM METİN
Kriz Dergisi; 2007;15(3):21-30
Psikonöroimmunoloji
Ö Bozo
ODTü Psikoloji Bölümü
Bu makalede yeni bir alan olan psikonöroimmünoloji'nin (PNI) ortaya çıkışı ve günümüze kadar bu alanda ne tür çalışmalar yapıldığı anlatılmıştır. Psikonöroimmünoloji, davranış, beyin ve bağışıklık sisteminin etkileşimini inceleyen alan olarak tanımlanmaktadır. Bu alandaki ilk çalışma bağışıklık sistemi işlevlerinin klasik koşullama ile değiştirilebileceğini ispatlamıştır. Bu alandaki diğer çalışmalar da göstermiştir ki; öğrenme beynin fonksiyonlarından biri olduğu için beyin ve bağışıklık sistemi arasında bir bağlantı vardır. Bağışıklık sistemi ve merkezi sinir sistemi ve dolayısıyla öğrenme süreçleri arasında bağlantı olduğu hem deney hayvanları hem de insanlarda yapılan çalışmalarla kanıtlanmıştır. Psikonöroimmünoloji beyin ve bağışıklık sistemi arasındaki bağı inceleyen alan olarak tanımlandığından, bu bağın kuramsal sonucu olarak, stres gibi psikolojik deneyimlerin bağışıklık sisteminin işlevleri üzerinde etkili olabileceği, bunun da hastalık süreci üzerinde bir etkisi bileceği belirtilmiştir. Bu bağlamda, bu makalede stresin beyne ve bilişe, nasıl ve ne zaman zararlı olduğu tartışılmıştır. Son olarak, günümüzde oldukça popüler bir alan psikonöroimmünolojiyi bekleyen tehlikeler ve bu alanda çalışan araştırmacıların bilim sınırları içerisinde kalmak için neler yapmaları gerektiği tartışılmıştır.
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Psychoneuroimmunology
This article explains the emergence of a new area, psychoneuroimmunology (PNI) and discusses the studies conducted in this area. Psychoneuroimmunology is defined as the study of interactions between behavior, brain, and immune system. The first study in this area proved that immune responses can be changed by classical conditioning. Other studies in this area showed that since learning is one of the functions of brain, they did prove the connection between brain and immune system. The connection between the immune system and thebrain was shown by many convincing findings of both human and animal studies. Since PNI is defined as the study of connection between the brain and the immune system, the theoretical consequence of that link is that psychological experiences, like stress, can have an effect on the immune function, which in turn may have an effect on the disease course. Thus, this article discusses how and when the stress affects the brain and cognition. Finally, the frightening sides of the popularity of psychoneuroimmunology and the points that needs to be paid attention in order to stay in the limits of the 'science' are discussed.

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